1AXI

STRUCTURAL PLASTICITY AT THE HGH:HGHBP INTERFACE

Summary for 1AXI

DescriptorGROWTH HORMONE, GROWTH HORMONE RECEPTOR, SULFATE ION, ... (4 entities in total)
Functional Keywordscomplex (hormone-receptor), complex (hormone-receptor) complex, complex (hormone/receptor)
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01241
Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Growth hormone-binding protein: Secreted P10912
Total number of polymer chains2
Total molecular weight49349.44
Authors
Atwell, S.,Ultsch, M.,De Vos, A.M.,Wells, J.A. (deposition date: 1997-10-15, release date: 1998-01-28, Last modification date: 2011-07-13)
Primary citation
Atwell, S.,Ultsch, M.,De Vos, A.M.,Wells, J.A.
Structural plasticity in a remodeled protein-protein interface.
Science, 278:1125-1128, 1997
PubMed: 9353194 (PDB entries with the same primary citation)
DOI: 10.1126/science.278.5340.1125
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers70.6%7.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload