1AXI

STRUCTURAL PLASTICITY AT THE HGH:HGHBP INTERFACE

Summary for 1AXI

• Entry DOI: 10.2210/pdb1axi/pdb
• Descriptor: GROWTH HORMONE, GROWTH HORMONE RECEPTOR, SULFATE ION, ... (4 entities in total)
• Functional Keywords: complex (hormone-receptor), complex (hormone-receptor) complex, complex (hormone/receptor)
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01241; Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Growth hormone-binding protein: Secreted: P10912
• Total number of polymer chains: 2
• Total formula weight: 49349.44

Authors

Atwell, S.,Ultsch, M.,De Vos, A.M.,Wells, J.A. (deposition date: 1997-10-15, release date: 1998-01-28, Last modification date: 2024-04-03)

• Primary citation: Atwell, S.,Ultsch, M.,De Vos, A.M.,Wells, J.A.; Structural plasticity in a remodeled protein-protein interface.; Science, 278:1125-1128, 1997; PubMed: 9353194; DOI: 10.1126/science.278.5340.1125

Experimental method

X-RAY DIFFRACTION (2.1 Å)