5N48

Structure of Anticalin N9B in complex with extra-domain B of human oncofetal fibronectin

Summary for 5N48

Entry DOI	10.2210/pdb5n48/pdb
Related	4gh7 5n47
Descriptor	Neutrophil gelatinase-associated lipocalin, Fibronectin (3 entities in total)
Functional Keywords	lipocalin, anticalin, lipocalin-based binding protein, protein binding, human fibronectin, oncofetal splice variant, fn type iii domain, extra-domain b, eiiib, ed-b, extracellular matrix
Biological source	Homo sapiens (Human) More
Cellular location	Secreted : P80188 Secreted, extracellular space, extracellular matrix: P02751
Total number of polymer chains	4
Total formula weight	65988.48
Authors	Schiefner, A.,Skerra, A. (deposition date: 2017-02-10, release date: 2018-02-14, Last modification date: 2024-01-17)
Primary citation	Schiefner, A.,Gebauer, M.,Richter, A.,Skerra, A. Anticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen. Structure, 26:649-656.e3, 2018 Cited by PubMed: 29526433 DOI: 10.1016/j.str.2018.02.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation