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6BFI
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BU of 6bfi by Molmil
Vinculin homolog in a sponge (phylum Porifera) reveals vertebrate-like cell adhesions involved in early multicellular evolution
Descriptor: VIN1
Authors:Weis, W.I, Chodaparambil, J.V.
Deposit date:2017-10-26
Release date:2018-06-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Analysis of a vinculin homolog in a sponge (phylum Porifera) reveals that vertebrate-like cell adhesions emerged early in animal evolution.
J. Biol. Chem., 293, 2018
5Y04
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BU of 5y04 by Molmil
Crystal Structure of the complex between the vinculin D1 domain and alphaE-catenin
Descriptor: Catenin alpha-1, Vinculin
Authors:Hirano, Y, Hakoshima, T.
Deposit date:2017-07-14
Release date:2018-03-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form
Genes Cells, 23, 2018
1H6G
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BU of 1h6g by Molmil
alpha-catenin M-domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-1 CATENIN, CALCIUM ION, ...
Authors:Yang, J, Dokurno, P, Tonks, N.K, Barford, D.
Deposit date:2001-06-14
Release date:2001-08-07
Last modified:2016-02-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the M-Fragment of Alpha-Catenin: Implications for Modulation of Cell Adhesion.
Embo J., 20, 2001
5H5M
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BU of 5h5m by Molmil
Crystal structure of HMP-1 M domain
Descriptor: Alpha-catenin-like protein hmp-1
Authors:Kang, H, Bang, I, Weis, W.I, Choi, H.J.
Deposit date:2016-11-08
Release date:2017-03-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional characterization of Caenorhabditis elegans alpha-catenin reveals constitutive binding to beta-catenin and F-actin
J. Biol. Chem., 292, 2017
1L7C
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BU of 1l7c by Molmil
alpha-catenin fragment, residues 385-651
Descriptor: Alpha E-catenin
Authors:Pokutta, S, Drees, F, Takai, Y, Nelson, W.J, Weis, W.I.
Deposit date:2002-03-14
Release date:2002-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin.
J.Biol.Chem., 277, 2002
1QKR
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BU of 1qkr by Molmil
Crystal structure of the vinculin tail and a pathway for activation
Descriptor: SULFATE ION, VINCULIN
Authors:Bakolitsa, C, De Pereda, J.M, Bagshaw, C.R, Critchley, D.R, Liddington, R.C.
Deposit date:1999-08-04
Release date:2000-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Vinculin Tail and a Pathway for Activation
Cell(Cambridge,Mass.), 99, 1999
4IGG
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BU of 4igg by Molmil
Full-length human alpha-catenin crystal structure
Descriptor: Catenin alpha-1, PHOSPHATE ION
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2012-12-17
Release date:2012-12-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.66 Å)
Cite:Dimer asymmetry defines alpha-catenin interactions.
Nat.Struct.Mol.Biol., 20, 2013
3MYI
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BU of 3myi by Molmil
Human metavinculin tail domain
Descriptor: Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A helix replacement mechanism directs metavinculin functions.
Plos One, 5, 2010
6DUW
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BU of 6duw by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
Descriptor: Catenin alpha-2
Authors:Ishiyama, N, Ikura, M.
Deposit date:2018-06-22
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
6DUY
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BU of 6duy by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
Descriptor: Catenin alpha-2
Authors:Ishiyama, N, Ikura, M.
Deposit date:2018-06-22
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
5XA5
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BU of 5xa5 by Molmil
Crystal structure of HMP-1-HMP-2 complex
Descriptor: Alpha-catenin-like protein hmp-1, Beta-catenin-like protein hmp-2
Authors:Shao, X, Kang, H, Weis, W.I, Hardin, J, Choi, H.J.
Deposit date:2017-03-11
Release date:2017-08-30
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the alpha-catenin· beta-catenin-binding interface.
J.Biol.Chem., 292, 2017
5XFL
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BU of 5xfl by Molmil
Crystal structure of the force-sensing device region of alpha N-catenin
Descriptor: Catenin alpha-2
Authors:Hirano, Y, Hakoshima, T.
Deposit date:2017-04-10
Release date:2018-03-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form
Genes Cells, 23, 2018
4K1O
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BU of 4k1o by Molmil
Crystal structure of the alphaN-catenin actin-binding domain
Descriptor: Catenin alpha-2, SULFATE ION
Authors:Ishiyama, N, Ikura, M.
Deposit date:2013-04-05
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:An autoinhibited structure of alpha-catenin and its implications for vinculin recruitment to adherens junctions.
J.Biol.Chem., 288, 2013
6FQ4
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BU of 6fq4 by Molmil
Structure of Chlamydial virulence factor TarP and vinculin head domain
Descriptor: TarP-VBS1, Vinculin
Authors:Whitewood, A.J, Singh, A.K, Brown, D.G, Goult, B.T.
Deposit date:2018-02-13
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex.
FEBS Lett., 592, 2018
6FUY
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BU of 6fuy by Molmil
Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066)
Descriptor: CALCIUM ION, Vinculin
Authors:Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B.
Deposit date:2018-02-28
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Conformational states during vinculin unlocking differentially regulate focal adhesion properties.
Sci Rep, 8, 2018
3ZDL
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BU of 3zdl by Molmil
Vinculin head (1-258) in complex with a RIAM fragment
Descriptor: AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN, VINCULIN
Authors:Zacharchenko, T, Elliott, P.R, Goult, B.T, Bate, N, Critchely, D.R, Barsukov, I.L.
Deposit date:2012-11-28
Release date:2013-02-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Riam and Vinculin Binding to Talin are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
6NR7
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BU of 6nr7 by Molmil
Rerefinement of chicken vinculin
Descriptor: (1R,2R,3S,4R,5R,6S)-4-{[(S)-[(2S)-2,3-dihydroxypropoxy](hydroxy)phosphoryl]oxy}-3,5,6-trihydroxycyclohexane-1,2-diyl bis[dihydrogen (phosphate)], PHOSPHATE ION, SULFATE ION, ...
Authors:Stec, B.
Deposit date:2019-01-23
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Refined model of chicken vinculin suggests the mechanism of activation by helical super-bundle unfurling
To be published
6O3E
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BU of 6o3e by Molmil
mouse aE-catenin 82-883
Descriptor: Catenin alpha-1
Authors:Pokutta, S, Weis, W.I.
Deposit date:2019-02-26
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.001 Å)
Cite:Binding partner- and force-promoted changes in alpha E-catenin conformation probed by native cysteine labeling.
Sci Rep, 9, 2019
4K1N
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BU of 4k1n by Molmil
Crystal structure of full-length mouse alphaE-catenin
Descriptor: Catenin alpha-1
Authors:Ishiyama, N, Ikura, M.
Deposit date:2013-04-05
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:An autoinhibited structure of alpha-catenin and its implications for vinculin recruitment to adherens junctions.
J.Biol.Chem., 288, 2013
4ONS
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BU of 4ons by Molmil
Structural and thermodynamic characterization of cadherin-beta-catenin-alpha-catenin complex formation
Descriptor: Catenin alpha-2, Catenin beta-1
Authors:Pokutta, S, Choi, H.-J, Ahlsen, G, Hansen, S.D, Weis, W.I.
Deposit date:2014-01-29
Release date:2014-04-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Thermodynamic Characterization of Cadherin beta-Catenin alpha-Catenin Complex Formation.
J.Biol.Chem., 289, 2014
4P9T
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BU of 4p9t by Molmil
Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin
Descriptor: 1,2-ETHANEDIOL, Catenin alpha-2, DI(HYDROXYETHYL)ETHER, ...
Authors:Shibahara, T, Hirano, Y, Hakoshima, T.
Deposit date:2014-04-04
Release date:2015-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin.
Febs Lett., 589, 2015
4PR9
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BU of 4pr9 by Molmil
Human Vinculin (residues 891-1066) in complex with PIP
Descriptor: GLYCEROL, Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Chinthalapudi, K, Rangarajan, E.S, Patil, D, Izard, T.
Deposit date:2014-03-05
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mechanism and function of lipid-directed oligomerization of vinculin
To be Published
4DJ9
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BU of 4dj9 by Molmil
Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50 (VBS50, residues 2078-2099)
Descriptor: Talin-1, Vinculin
Authors:Yogesha, S.D, Rangarajan, E.S, Vonrhein, C, Bricogne, G, Izard, T.
Deposit date:2012-02-01
Release date:2012-02-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin.
Protein Sci., 21, 2012
4E18
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BU of 4e18 by Molmil
Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin
Descriptor: Catenin alpha-1, Vinculin
Authors:Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I.
Deposit date:2012-03-05
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
3S90
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BU of 3s90 by Molmil
Human vinculin head domain Vh1 (residues 1-252) in complex with murine talin (VBS33; residues 1512-1546)
Descriptor: Talin-1, Vinculin
Authors:Yogesha, S.D, Sharff, A, Bricogne, G, Izard, T.
Deposit date:2011-05-31
Release date:2011-06-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin.
Protein Sci., 20, 2011

 

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