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6KVG
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BU of 6kvg by Molmil
The solution structure of human Orc6
Descriptor: Origin recognition complex subunit 6
Authors:Liu, C, Xu, N, You, Y, Zhu, G.
Deposit date:2019-09-04
Release date:2020-09-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA.
Nucleic Acids Res., 48, 2020
8U1N
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BU of 8u1n by Molmil
Cryo-EM structure of the cross-linked HSP90 dimer (NTD-MD) in the semi-open state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, MAGNESIUM ION
Authors:Finci, L.I, Simanshu, D.K.
Deposit date:2023-09-01
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.
Commun Biol, 7, 2024
8TLT
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BU of 8tlt by Molmil
Cryo-EM structure of Rev1(deltaN)-Polzeta-DNA-dCTP complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*TP*AP*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*AP*AP*T)-3'), ...
Authors:Malik, R, Aggarwal, A.K.
Deposit date:2023-07-27
Release date:2024-05-15
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis.
Nat.Struct.Mol.Biol., 31, 2024
8TLQ
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BU of 8tlq by Molmil
Cryo-EM structure of the Rev1-Polzeta-DNA-dCTP complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ...
Authors:Malik, R, Aggarwal, A.K.
Deposit date:2023-07-27
Release date:2024-05-15
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis.
Nat.Struct.Mol.Biol., 31, 2024
8TPQ
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BU of 8tpq by Molmil
nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (long TM6)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TOK
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BU of 8tok by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ (open state)
Descriptor: CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-03
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPR
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BU of 8tpr by Molmil
nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (short TM6)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPM
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BU of 8tpm by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPS
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BU of 8tps by Molmil
nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (bent TM6)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPN
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BU of 8tpn by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ (intermediate state)
Descriptor: CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TOL
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BU of 8tol by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (open state)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-03
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TOI
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BU of 8toi by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (closed state)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-03
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPP
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BU of 8tpp by Molmil
nhTMEM16 R432A mutant in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+
Descriptor: CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPT
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BU of 8tpt by Molmil
nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (long TM6/short TM6)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TNJ
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BU of 8tnj by Molmil
Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs
Descriptor: 9mer peptide,Beta-2-microglobulin,MHC class I antigen chimera, B.1 Fab heavy chain, B.1 Fab light chain, ...
Authors:Ross, P, Adams, E.J, Lodwick, J, Zhao, M, Slezak, T, Kossiakoff, A.
Deposit date:2023-08-02
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs
To Be Published
7Y1Q
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BU of 7y1q by Molmil
5.0 angstrom cryo-EM structure of transmembrane regions of mouse Basigin/MCT1 in complex with antibody 6E7F1
Descriptor: Isoform 2 of Basigin, Monocarboxylate transporter 1
Authors:Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J.
Deposit date:2022-06-08
Release date:2023-06-14
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (5.03 Å)
Cite:Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin-2
To Be Published
8TKQ
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BU of 8tkq by Molmil
Cryo-EM structure of human full-length RAD52
Descriptor: DNA repair protein RAD52 homolog
Authors:Schnicker, N.J, Razzaghi, M, Spies, M.
Deposit date:2023-07-25
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:A double-ring of human RAD52 remodels replication forks restricting fork reversal
To Be Published
8U5V
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BU of 8u5v by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155) - auxin bound, closed state
Descriptor: 1H-INDOL-3-YLACETIC ACID, CHOLESTEROL HEMISUCCINATE, Integral membrane protein GPR155
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-13
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:The structure of GPR155
To Be Published
8U5X
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BU of 8u5x by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155) - auxin bound, open state
Descriptor: 1H-INDOL-3-YLACETIC ACID, Integral membrane protein GPR155
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-13
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:The structure of GPR155
To Be Published
8U1H
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BU of 8u1h by Molmil
Axle-less Bacillus sp. PS3 F1 ATPase mutant
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP synthase gamma chain, ATP synthase subunit alpha, ...
Authors:Furlong, E.J, Zeng, Y.C, Brown, S.H.J, Sobti, M, Stewart, A.G.
Deposit date:2023-09-01
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The molecular structure of an axle-less F1 ATPase
To Be Published
8UDG
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BU of 8udg by Molmil
S1V2-72 Fab bound to EHA2 from influenza B/Malaysia/2506/2004
Descriptor: Hemagglutinin, S1V2-72 heavy chain, S1V2-72 light chain
Authors:Finney, J, Kong, S, Walsh Jr, R.M, Harrison, S.C, Kelsoe, G.
Deposit date:2023-09-28
Release date:2023-11-15
Last modified:2024-01-10
Method:ELECTRON MICROSCOPY (4.98 Å)
Cite:Protective human antibodies against a conserved epitope in pre- and postfusion influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UXL
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BU of 8uxl by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8UX1
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BU of 8ux1 by Molmil
Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle
Descriptor: 153-bp Widom 601 DNA forward strand, 153-bp Widom 601 DNA reverse strand, GTP-binding nuclear protein Ran, ...
Authors:Huang, S.K, Rubinstein, J.L, Kay, L.E.
Deposit date:2023-11-08
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle
To Be Published
8UXM
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BU of 8uxm by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8UR3
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BU of 8ur3 by Molmil
Cryo-EM reconstruction of Staphylococcus aureus Oleate hydratase (OhyA) dimer with an ordered C-terminal membrane-association domain
Descriptor: Oleate hydratase
Authors:Oldham, M.L, Qayyum, M.Z.
Deposit date:2023-10-25
Release date:2024-01-10
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer.
J.Biol.Chem., 300, 2024

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数据于2024-10-09公开中

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