7Y1Q

5.0 angstrom cryo-EM structure of transmembrane regions of mouse Basigin/MCT1 in complex with antibody 6E7F1

Summary for 7Y1Q

• Entry DOI: 10.2210/pdb7y1q/pdb
• Related: 7Y1B
• EMDB information: 33570
• Descriptor: Monocarboxylate transporter 1, Isoform 2 of Basigin (2 entities in total)
• Functional Keywords: transporter, glucose metabolism, monocarboxylic acid transport, alpha helical tms, transport protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 83016.33

Authors

Zhang, H.,Yang, X.,Xue, Y.,Huang, Y.,Mo, X.,Zhang, H.,Li, N.,Gao, N.,Li, X.,Wang, S.,Gao, Y.,Liao, J. (deposition date: 2022-06-08, release date: 2023-06-14, Last modification date: 2024-07-03)

• Primary citation: Zhang, H.,Yang, X.,Xue, Y.,Huang, Y.,Mo, Y.,Zhang, H.,Li, N.,Gao, N.,Li, X.,Wang, S.,Gao, Y.,Liao, J.; Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin-2; To Be Published,

Experimental method

ELECTRON MICROSCOPY (5.03 Å)