8TPM

nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+

Summary for 8TPM

Entry DOI	10.2210/pdb8tpm/pdb
EMDB information	41477
Descriptor	Lipid scramblase nhTMEM16, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate (2 entities in total)
Functional Keywords	membrane protein, lipid scramblase, tmem16, lipid transport
Biological source	Fusarium vanettenii 77-13-4
Total number of polymer chains	2
Total formula weight	177074.22
Authors	Feng, Z.,Accardi, A. (deposition date: 2023-08-04, release date: 2024-05-08)
Primary citation	Feng, Z.,Alvarenga, O.E.,Accardi, A. Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38684930 DOI: 10.1038/s41594-024-01284-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.93 Å)

Structure validation