8TLT

Cryo-EM structure of Rev1(deltaN)-Polzeta-DNA-dCTP complex

Summary for 8TLT

• Entry DOI: 10.2210/pdb8tlt/pdb
• EMDB information: 41372
• Descriptor: DNA polymerase zeta catalytic subunit, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase zeta processivity subunit, ... (11 entities in total)
• Functional Keywords: dna repair, dna replication, translesion dna synthesis, dna polymerase, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Saccharomyces cerevisiae (brewer's yeast); More
• Total number of polymer chains: 8
• Total formula weight: 453463.98

Authors

Malik, R.,Aggarwal, A.K. (deposition date: 2023-07-27, release date: 2024-05-15, Last modification date: 2024-05-22)

• Primary citation: Malik, R.,Johnson, R.E.,Ubarretxena-Belandia, I.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis.; Nat.Struct.Mol.Biol., 2024; PubMed: 38720088; DOI: 10.1038/s41594-024-01302-w

Experimental method

ELECTRON MICROSCOPY (2.85 Å)