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8TLT

Cryo-EM structure of Rev1(deltaN)-Polzeta-DNA-dCTP complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0000724biological_processdouble-strand break repair via homologous recombination
A0003676molecular_functionnucleic acid binding
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005739cellular_componentmitochondrion
A0006260biological_processDNA replication
A0006281biological_processDNA repair
A0006974biological_processDNA damage response
A0008270molecular_functionzinc ion binding
A0016035cellular_componentzeta DNA polymerase complex
A0019985biological_processtranslesion synthesis
A0034061molecular_functionDNA polymerase activity
A0042276biological_processerror-prone translesion synthesis
A0043231cellular_componentintracellular membrane-bounded organelle
A0046872molecular_functionmetal ion binding
A0051539molecular_function4 iron, 4 sulfur cluster binding
A0070987biological_processerror-free translesion synthesis
B0000785cellular_componentchromatin
B0003677molecular_functionDNA binding
B0003684molecular_functiondamaged DNA binding
B0003887molecular_functionDNA-directed DNA polymerase activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005657cellular_componentreplication fork
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0006281biological_processDNA repair
B0016779molecular_functionnucleotidyltransferase activity
B0017125molecular_functiondeoxycytidyl transferase activity
B0042276biological_processerror-prone translesion synthesis
B0043231cellular_componentintracellular membrane-bounded organelle
B0046872molecular_functionmetal ion binding
B0070987biological_processerror-free translesion synthesis
B0071897biological_processDNA biosynthetic process
D0000785cellular_componentchromatin
D0003887molecular_functionDNA-directed DNA polymerase activity
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005739cellular_componentmitochondrion
D0006281biological_processDNA repair
D0016035cellular_componentzeta DNA polymerase complex
D0042276biological_processerror-prone translesion synthesis
D0070987biological_processerror-free translesion synthesis
E0000785cellular_componentchromatin
E0003887molecular_functionDNA-directed DNA polymerase activity
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005739cellular_componentmitochondrion
E0006281biological_processDNA repair
E0016035cellular_componentzeta DNA polymerase complex
E0042276biological_processerror-prone translesion synthesis
E0070987biological_processerror-free translesion synthesis
F0003677molecular_functionDNA binding
F0003887molecular_functionDNA-directed DNA polymerase activity
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005829cellular_componentcytosol
F0006259biological_processDNA metabolic process
F0006260biological_processDNA replication
F0006271biological_processDNA strand elongation involved in DNA replication
F0006272biological_processleading strand elongation
F0006273biological_processlagging strand elongation
F0006278biological_processRNA-templated DNA biosynthetic process
F0006284biological_processbase-excision repair
F0006289biological_processnucleotide-excision repair
F0006298biological_processmismatch repair
F0006301biological_processpostreplication repair
F0008310molecular_functionsingle-stranded DNA 3'-5' DNA exonuclease activity
F0016035cellular_componentzeta DNA polymerase complex
F0034061molecular_functionDNA polymerase activity
F0043137biological_processDNA replication, removal of RNA primer
F0043625cellular_componentdelta DNA polymerase complex
G0000510molecular_functionH3-H4 histone complex chaperone activity
G0000727biological_processdouble-strand break repair via break-induced replication
G0003887molecular_functionDNA-directed DNA polymerase activity
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0006259biological_processDNA metabolic process
G0006260biological_processDNA replication
G0006272biological_processleading strand elongation
G0006273biological_processlagging strand elongation
G0006277biological_processDNA amplification
G0006278biological_processRNA-templated DNA biosynthetic process
G0006284biological_processbase-excision repair
G0006289biological_processnucleotide-excision repair
G0008310molecular_functionsingle-stranded DNA 3'-5' DNA exonuclease activity
G0016035cellular_componentzeta DNA polymerase complex
G0042276biological_processerror-prone translesion synthesis
G0043137biological_processDNA replication, removal of RNA primer
G0043625cellular_componentdelta DNA polymerase complex
Functional Information from PROSITE/UniProt
site_idPS00116
Number of Residues9
DetailsDNA_POLYMERASE_B DNA polymerase family B signature. YGDTDSLFV
ChainResidueDetails
ATYR1140-VAL1148

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22814378
ChainResidueDetails
FMET1
BSER402
BASN414

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
FSER20
BPHE363
BASP467
BGLU468
ACYS1446
ACYS1449
ACYS1468
ACYS1473

site_idSWS_FT_FI3
Number of Residues3
DetailsSITE: Interaction with target DNA
ChainResidueDetails
BLYS681
BSER692
BSER694

227111

PDB entries from 2024-11-06

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