1SGN
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![BU of 1sgn by Molmil](/molmil-images/mine/1sgn) | ASN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B | Descriptor: | Ovomucoid, PHOSPHATE ION, Streptogrisin B | Authors: | Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G. | Deposit date: | 1999-03-25 | Release date: | 2003-08-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with
Streptomyces griseus Protease B at Various pHs To be Published
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6E2A
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![BU of 6e2a by Molmil](/molmil-images/mine/6e2a) | Crystal structure of NADH:quinone reductase PA1024 from Pseudomonas aeruginosa PAO1 in complex with NAD+ | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Reis, R.A.G, Ball, J, Agniswamy, J, Weber, I, Gadda, G. | Deposit date: | 2018-07-10 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Steric hindrance controls pyridine nucleotide specificity of a flavin-dependent NADH:quinone oxidoreductase. Protein Sci., 28, 2019
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4PZF
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![BU of 4pzf by Molmil](/molmil-images/mine/4pzf) | Berberine bridge enzyme G164A variant, a reticuline dehydrogenase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DODECAETHYLENE GLYCOL, ... | Authors: | Zafred, D, Wallner, S, Steiner, B, Macheroux, P. | Deposit date: | 2014-03-30 | Release date: | 2014-04-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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8DES
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![BU of 8des by Molmil](/molmil-images/mine/8des) | Gokushovirus EC6098 | Descriptor: | Major capsid protein, Putative DNA binding protein | Authors: | Lee, H, Fane, B.A, Hafenstein, S.L. | Deposit date: | 2022-06-21 | Release date: | 2022-10-12 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Cryo-EM Structure of Gokushovirus Phi EC6098 Reveals a Novel Capsid Architecture for a Single-Scaffolding Protein, Microvirus Assembly System. J.Virol., 96, 2022
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6E2H
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![BU of 6e2h by Molmil](/molmil-images/mine/6e2h) | |
4V9Q
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![BU of 4v9q by Molmil](/molmil-images/mine/4v9q) | Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svidritskiy, E, Ling, C, Ermolenko, D.N, Korostelev, A.A. | Deposit date: | 2013-06-12 | Release date: | 2014-07-09 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc.Natl.Acad.Sci.USA, 110, 2013
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1WTC
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![BU of 1wtc by Molmil](/molmil-images/mine/1wtc) | Crystal Structure of S.pombe Serine Racemase complex with AMPPCP | Descriptor: | Hypothetical protein C320.14 in chromosome III, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Goto, M, Miyahara, I, Hirotsu, K. | Deposit date: | 2004-11-22 | Release date: | 2005-11-01 | Last modified: | 2014-05-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a homolog of mammalian serine racemase from Schizosaccharomyces pombe J.Biol.Chem., 284, 2009
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6EB1
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![BU of 6eb1 by Molmil](/molmil-images/mine/6eb1) | HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-1-phenylisoquinolin-4-yl]acetic acid | Descriptor: | (2S)-tert-butoxy[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-1-phenylisoquinolin-4-yl]acetic acid, Integrase | Authors: | Lindenberger, J.J, Kobe, M, Kvaratskhelia, M. | Deposit date: | 2018-08-03 | Release date: | 2019-03-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | An Isoquinoline Scaffold as a Novel Class of Allosteric HIV-1 Integrase Inhibitors. ACS Med Chem Lett, 10, 2019
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1R7H
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2RV2
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![BU of 2rv2 by Molmil](/molmil-images/mine/2rv2) | Solution structures of the DNA-binding domain (ZF14) of immune-related zinc-finger protein ZFAT | Descriptor: | ZINC ION, Zinc finger protein ZFAT | Authors: | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | Deposit date: | 2015-01-26 | Release date: | 2015-04-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT J.Struct.Funct.Genom., 16, 2015
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6E2S
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![BU of 6e2s by Molmil](/molmil-images/mine/6e2s) | apo form of MDDEF with buffer exchange | Descriptor: | Mevalonate diphosphate decarboxylase, SULFATE ION | Authors: | Stauffacher, C.V, Chen, C.-L. | Deposit date: | 2018-07-12 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.791 Å) | Cite: | Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11, 2020
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4V4Q
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![BU of 4v4q by Molmil](/molmil-images/mine/4v4q) | Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D. | Deposit date: | 2005-08-30 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | Structures of the bacterial ribosome at 3.5 A resolution. Science, 310, 2005
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2R51
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![BU of 2r51 by Molmil](/molmil-images/mine/2r51) | Crystal Structure of mouse Vps26B | Descriptor: | Vacuolar protein sorting-associated protein 26B | Authors: | Owen, D.J, Teasdale, R.D, Collins, B.M. | Deposit date: | 2007-09-02 | Release date: | 2008-07-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Vps26B and mapping of its interaction with the retromer protein complex. Traffic, 9, 2008
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6E2T
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![BU of 6e2t by Molmil](/molmil-images/mine/6e2t) | MDDEF in complex with MVAPP | Descriptor: | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Mevalonate diphosphate decarboxylase | Authors: | Stauffacher, C.V, Chen, C.-L. | Deposit date: | 2018-07-12 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.692 Å) | Cite: | Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11, 2020
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6E2U
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![BU of 6e2u by Molmil](/molmil-images/mine/6e2u) | MDDEF in complex with MVAPP, AMPPCP and Magnesium | Descriptor: | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, MAGNESIUM ION, Mevalonate diphosphate decarboxylase, ... | Authors: | Stauffacher, C.V, Chen, C.-L. | Deposit date: | 2018-07-12 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11, 2020
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6EDX
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![BU of 6edx by Molmil](/molmil-images/mine/6edx) | Crystal Structure of SGK3 PX domain | Descriptor: | GLYCEROL, Serine/threonine-protein kinase Sgk3 | Authors: | Chandra, M, Collins, B.M. | Deposit date: | 2018-08-12 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.009 Å) | Cite: | Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities. Nat Commun, 10, 2019
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2R9A
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![BU of 2r9a by Molmil](/molmil-images/mine/2r9a) | Crystal structure of human XLF | Descriptor: | Non-homologous end-joining factor 1 | Authors: | Andres, S.N, Junop, M.S. | Deposit date: | 2007-09-12 | Release date: | 2008-01-01 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Human XLF: A Twist in Nonhomologous DNA End-Joining Mol.Cell, 28
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6E2P
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6E2W
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![BU of 6e2w by Molmil](/molmil-images/mine/6e2w) | MDDEF in complex with MVAPP, ADP, sulfate and cobalt | Descriptor: | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ... | Authors: | Stauffacher, C.V, Chen, C.-L. | Deposit date: | 2018-07-12 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11, 2020
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2WN2
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![BU of 2wn2 by Molmil](/molmil-images/mine/2wn2) | Structure of the discoidin I from Dictyostelium discoideum in complex with galactose beta 1-3 galNAc at 1.8 A resolution. | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, ... | Authors: | Mathieu, S, Imberty, A, Varrot, A. | Deposit date: | 2009-07-07 | Release date: | 2010-05-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Discoidin I from Dictyostelium Discoideum and Interactions with Oligosaccharides: Specificity, Affinity, Crystal Structures and Comparison with Discoidin II. J.Mol.Biol., 400, 2010
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1R37
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![BU of 1r37 by Molmil](/molmil-images/mine/1r37) | Alcohol dehydrogenase from sulfolobus solfataricus complexed with NAD(H) and 2-ethoxyethanol | Descriptor: | 2-ETHOXYETHANOL, NAD-dependent alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Esposito, L, Bruno, I, Sica, F, Raia, C.A, Giordano, A, Rossi, M, Mazzarella, L, Zagari, A. | Deposit date: | 2003-09-30 | Release date: | 2004-02-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a ternary complex of the alcohol dehydrogenase from Sulfolobus solfataricus Biochemistry, 42, 2003
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2RKV
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![BU of 2rkv by Molmil](/molmil-images/mine/2rkv) | Crystal Structure of F. graminearum TRI101 complexed with Coenzyme A and T-2 mycotoxin | Descriptor: | 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, COENZYME A, ... | Authors: | Garvey, G.S, Rayment, I. | Deposit date: | 2007-10-17 | Release date: | 2007-12-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and Functional Characterization of the TRI101 Trichothecene 3-O-Acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: KINETIC INSIGHTS TO COMBATING FUSARIUM HEAD BLIGHT J.Biol.Chem., 283, 2008
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6EF0
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![BU of 6ef0 by Molmil](/molmil-images/mine/6ef0) | Yeast 26S proteasome bound to ubiquitinated substrate (1D* motor state) | Descriptor: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | Authors: | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | Deposit date: | 2018-08-15 | Release date: | 2018-10-17 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.43 Å) | Cite: | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science, 362, 2018
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4UV4
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![BU of 4uv4 by Molmil](/molmil-images/mine/4uv4) | Crystal structure of anti-FPR Fpro0165 Fab fragment | Descriptor: | FPRO0165 FAB | Authors: | Douthwaite, J.A, Sridharan, S, Huntington, C, Marwood, R, Hammersley, J, Hakulinen, J.K, Ek, M, Sjogren, T, Rider, D, Privezentzev, C, Seaman, J.C, Cariuk, P, Knights, V, Young, J, Wilkinson, T, Sleeman, M, Finch, D.K, Lowe, D.C, Vaughan, T.J. | Deposit date: | 2014-08-04 | Release date: | 2014-12-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.08 Å) | Cite: | Affinity Maturation of a Novel Antagonistic Human Monoclonal Antibody with a Long Vh Cdr3 Targeting the Class a Gpcr Formyl-Peptide Receptor 1. Mabs, 7, 2015
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6EGA
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![BU of 6ega by Molmil](/molmil-images/mine/6ega) | IRAK4 in complex with a type II inhibitor | Descriptor: | 3-{2-[(cyclopropanecarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(piperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide, COBALT (II) ION, Interleukin-1 receptor-associated kinase 4, ... | Authors: | Wang, L, Wu, H. | Deposit date: | 2018-08-19 | Release date: | 2019-02-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.512 Å) | Cite: | Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4). J.Biol.Chem., 294, 2019
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