4UV4
Crystal structure of anti-FPR Fpro0165 Fab fragment
Summary for 4UV4
Entry DOI | 10.2210/pdb4uv4/pdb |
Descriptor | FPRO0165 FAB (2 entities in total) |
Functional Keywords | immune system, antibody engineering, phage display, long cdr, formyl peptide receptor-1 |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 49953.84 |
Authors | Douthwaite, J.A.,Sridharan, S.,Huntington, C.,Marwood, R.,Hammersley, J.,Hakulinen, J.K.,Ek, M.,Sjogren, T.,Rider, D.,Privezentzev, C.,Seaman, J.C.,Cariuk, P.,Knights, V.,Young, J.,Wilkinson, T.,Sleeman, M.,Finch, D.K.,Lowe, D.C.,Vaughan, T.J. (deposition date: 2014-08-04, release date: 2014-12-24, Last modification date: 2024-01-10) |
Primary citation | Douthwaite, J.A.,Sridharan, S.,Huntington, C.,Hammersley, J.,Marwood, R.,Hakulinen, J.K.,Ek, M.,Sjogren, T.,Rider, D.,Privezentzev, C.,Seaman, J.C.,Cariuk, P.,Knights, V.,Young, J.,Wilkinson, T.,Sleeman, M.,Finch, D.K.,Lowe, D.C.,Vaughan, T.J. Affinity Maturation of a Novel Antagonistic Human Monoclonal Antibody with a Long Vh Cdr3 Targeting the Class a Gpcr Formyl-Peptide Receptor 1. Mabs, 7:152-, 2015 Cited by PubMed: 25484051DOI: 10.4161/19420862.2014.985158 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.08 Å) |
Structure validation
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