6E2U
MDDEF in complex with MVAPP, AMPPCP and Magnesium
Summary for 6E2U
| Entry DOI | 10.2210/pdb6e2u/pdb |
| Descriptor | Mevalonate diphosphate decarboxylase, (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (5 entities in total) |
| Functional Keywords | mevalonate diphosphate decarboxylase, lyase |
| Biological source | Enterococcus faecalis (Streptococcus faecalis) |
| Total number of polymer chains | 1 |
| Total formula weight | 40113.99 |
| Authors | Stauffacher, C.V.,Chen, C.-L. (deposition date: 2018-07-12, release date: 2020-01-15, Last modification date: 2023-10-11) |
| Primary citation | Chen, C.L.,Paul, L.N.,Mermoud, J.C.,Steussy, C.N.,Stauffacher, C.V. Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11:3969-3969, 2020 Cited by PubMed: 32769976DOI: 10.1038/s41467-020-17733-0 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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