6E2U
MDDEF in complex with MVAPP, AMPPCP and Magnesium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue DP6 A 401 |
| Chain | Residue |
| A | ALA13 |
| A | SER191 |
| A | ARG192 |
| A | MET195 |
| A | ASP282 |
| A | ALA283 |
| A | ACP402 |
| A | MG403 |
| A | HOH518 |
| A | HOH544 |
| A | TYR17 |
| A | LYS20 |
| A | LYS71 |
| A | SER106 |
| A | SER138 |
| A | GLY139 |
| A | SER140 |
| A | ARG143 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue ACP A 402 |
| Chain | Residue |
| A | THR42 |
| A | PHE57 |
| A | LEU59 |
| A | GLN68 |
| A | LYS71 |
| A | VAL72 |
| A | SER93 |
| A | ASN95 |
| A | ALA104 |
| A | SER105 |
| A | SER106 |
| A | GLY109 |
| A | SER190 |
| A | SER191 |
| A | ALA283 |
| A | DP6401 |
| A | MG403 |
| A | HOH521 |
| A | HOH532 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 403 |
| Chain | Residue |
| A | SER106 |
| A | DP6401 |
| A | ACP402 |
