6E2U

MDDEF in complex with MVAPP, AMPPCP and Magnesium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004163	molecular_function	diphosphomevalonate decarboxylase activity
A	0005829	cellular_component	cytosol
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016831	molecular_function	carboxy-lyase activity
A	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue DP6 A 401

Chain	Residue
A	ALA13
A	SER191
A	ARG192
A	MET195
A	ASP282
A	ALA283
A	ACP402
A	MG403
A	HOH518
A	HOH544
A	TYR17
A	LYS20
A	LYS71
A	SER106
A	SER138
A	GLY139
A	SER140
A	ARG143

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site_id	AC2
Number of Residues	19
Details	binding site for residue ACP A 402

Chain	Residue
A	THR42
A	PHE57
A	LEU59
A	GLN68
A	LYS71
A	VAL72
A	SER93
A	ASN95
A	ALA104
A	SER105
A	SER106
A	GLY109
A	SER190
A	SER191
A	ALA283
A	DP6401
A	MG403
A	HOH521
A	HOH532

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site_id	AC3
Number of Residues	3
Details	binding site for residue MG A 403

Chain	Residue
A	SER106
A	DP6401
A	ACP402

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