7PXG
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![BU of 7pxg by Molmil](/molmil-images/mine/7pxg) | Verruculogen-bound Drosophila Slo channel | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ... | Authors: | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | Deposit date: | 2021-10-08 | Release date: | 2021-12-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7PXF
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![BU of 7pxf by Molmil](/molmil-images/mine/7pxf) | Ca2+ free Drosophila Slo channel | Descriptor: | Isoform J of Calcium-activated potassium channel slowpoke, MAGNESIUM ION, POTASSIUM ION | Authors: | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | Deposit date: | 2021-10-08 | Release date: | 2021-12-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7PXE
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![BU of 7pxe by Molmil](/molmil-images/mine/7pxe) | Ca2+ bound Drosophila Slo channel | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ... | Authors: | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | Deposit date: | 2021-10-08 | Release date: | 2021-12-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7YTQ
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![BU of 7ytq by Molmil](/molmil-images/mine/7ytq) | |
6RZ6
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![BU of 6rz6 by Molmil](/molmil-images/mine/6rz6) | Crystal structure of the human cysteinyl leukotriene receptor 2 in complex with ONO-2570366 (C2221 space group) | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{S})-8-[[4-[4-(2-chloranyl-5-fluoranyl-phenyl)butoxy]phenyl]carbonylamino]-4-(4-oxidanyl-4-oxidanylidene-butyl)-2,3- dihydro-1,4-benzoxazine-2-carboxylic acid, CHOLESTEROL, ... | Authors: | Gusach, A, Luginina, A, Marin, E, Brouillette, R.L, Besserer-Offroy, E, Longpre, J.M, Ishchenko, A, Popov, P, Fujimoto, T, Maruyama, T, Stauch, B, Ergasheva, M, Romanovskaya, D, Stepko, A, Kovalev, K, Shevtsov, M, Gordeliy, V, Han, G.W, Sarret, P, Katritch, V, Borshchevskiy, V, Mishin, A, Cherezov, V. | Deposit date: | 2019-06-12 | Release date: | 2019-12-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors. Nat Commun, 10, 2019
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1UEQ
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![BU of 1ueq by Molmil](/molmil-images/mine/1ueq) | Solution Structure of The First PDZ domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 protein) | Descriptor: | MEMBRANE ASSOCIATED GUANYLATE KINASE INVERTED-2 (MAGI-2) | Authors: | Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-05-20 | Release date: | 2003-11-20 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structure of The First PDZ domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 protein) To be Published
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1UFW
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![BU of 1ufw by Molmil](/molmil-images/mine/1ufw) | Solution structure of RNP domain in Synaptojanin 2 | Descriptor: | Synaptojanin 2 | Authors: | He, F, Muto, Y, Ushikoshi, R, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Ohara, O, Nagase, T, Kikuno, R, Nakayama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-10 | Release date: | 2003-12-10 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of RNP domain in Synaptojanin 2 To be Published
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1UEP
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![BU of 1uep by Molmil](/molmil-images/mine/1uep) | Solution Structure of The Third PDZ Domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 Protein) | Descriptor: | Membrane Associated Guanylate Kinase Inverted-2 (MAGI-2) | Authors: | Miyamoto, K, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-05-20 | Release date: | 2003-11-20 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structure of The Third PDZ Domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 Protein) To be Published
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1ECN
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![BU of 1ecn by Molmil](/molmil-images/mine/1ecn) | |
7N9J
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![BU of 7n9j by Molmil](/molmil-images/mine/7n9j) | Crystal structure of H2DB in complex with HSF2 melanoma neoantigen | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | Authors: | Patskovsky, Y, Finnigan, J, Patskovska, L, Newman, J, Bhardwaj, N, Krogsgaard, M. | Deposit date: | 2021-06-18 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structure of the complex between H2DB and melanoma HSF2 neoantigen YGFRNVVHI To be Published
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7NA5
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![BU of 7na5 by Molmil](/molmil-images/mine/7na5) | Structure of the H2DB-TCR ternary complex with HSF2 melanoma neoantigen | Descriptor: | 47BE7 TCR alpha chain, 47BE7 TCR beta chain, Beta-2-microglobulin, ... | Authors: | Patskovsky, Y, Finnigan, J, Patskovska, L, Newman, J, Bhardwaj, N, Krogsgaard, M. | Deposit date: | 2021-06-19 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the TCR-H2DB ternary complex with melanoma HSF2 neoantigen YGFRNVVHI To be Published
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8C2D
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![BU of 8c2d by Molmil](/molmil-images/mine/8c2d) | 14-3-3 in complex with Pyrin pS208 | Descriptor: | 14-3-3 protein sigma, MAGNESIUM ION, Pyrin pS208 peptide | Authors: | Lau, R, Ottmann, C, Hann, M. | Deposit date: | 2022-12-22 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure and ligandability of the 14-3-3/pyrin interface. Biochem.Biophys.Res.Commun., 651, 2023
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7W2B
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7W2C
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![BU of 7w2c by Molmil](/molmil-images/mine/7w2c) | The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 | Descriptor: | 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate, GOLD ION, Sigma non-opioid intracellular receptor 1, ... | Authors: | Meng, F, Sun, Z, Zhou, X. | Deposit date: | 2021-11-23 | Release date: | 2022-03-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.335 Å) | Cite: | An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway. Nat Commun, 13, 2022
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7W2E
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7W2G
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7W2H
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7W2D
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![BU of 7w2d by Molmil](/molmil-images/mine/7w2d) | |
7W2F
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7Z3Y
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![BU of 7z3y by Molmil](/molmil-images/mine/7z3y) | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH013545 | Descriptor: | 2-[4-(3,5-dimethylpyrazol-1-yl)-2,6-bis(fluoranyl)phenyl]-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)ethanamide, GLYCEROL, N-glycosylase/DNA lyase, ... | Authors: | Scaletti, E.R, Stenmark, P. | Deposit date: | 2022-03-02 | Release date: | 2023-03-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH013545 To Be Published
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7Z5B
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![BU of 7z5b by Molmil](/molmil-images/mine/7z5b) | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH013546 | Descriptor: | 2-[4-(2,4-dimethyl-1~{H}-imidazol-5-yl)phenyl]-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)ethanamide, N-glycosylase/DNA lyase, NICKEL (II) ION | Authors: | Scaletti, E, Stenmark, P. | Deposit date: | 2022-03-08 | Release date: | 2023-03-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH013546 To Be Published
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7Z5R
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![BU of 7z5r by Molmil](/molmil-images/mine/7z5r) | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012035 | Descriptor: | (7~{R})-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)bicyclo[4.2.0]octa-1,3,5-triene-7-carboxamide, N-glycosylase/DNA lyase, NICKEL (II) ION | Authors: | Davies, J.R, Scaletti, E, Stenmark, P. | Deposit date: | 2022-03-09 | Release date: | 2023-03-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012035 To Be Published
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7PJH
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![BU of 7pjh by Molmil](/molmil-images/mine/7pjh) | Crystal structure of the human spliceosomal maturation factor AAR2 bound to the RNAse H domain of PRPF8 | Descriptor: | Pre-mRNA-processing-splicing factor 8, Protein AAR2 homolog | Authors: | Preussner, M, Santos, K, Heroven, A.C, Alles, J, Heyd, F, Wahl, M.C, Weber, G. | Deposit date: | 2021-08-24 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8. Acta Crystallogr D Struct Biol, 78, 2022
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1B9K
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1UDM
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![BU of 1udm by Molmil](/molmil-images/mine/1udm) | Solution structure of Coactosin-like protein (Cofilin family) from Mus Musculus | Descriptor: | Coactosin-like protein | Authors: | Goroncy, A.K, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-05-01 | Release date: | 2004-05-18 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR solution structures of actin depolymerizing factor homology domains. Protein Sci., 18, 2009
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