4MQE

Crystal structure of the extracellular domain of human GABA(B) receptor in the apo form

Summary for 4MQE

Entry DOI	10.2210/pdb4mqe/pdb
Related	4MQF 4MR7 4MR8 4MR9 4MRM 4MS1 4MS3 4MS4
Descriptor	Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	heterodimeric protein complex, venus flytrap module, neurotransmitter receptor, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	98783.99
Authors	Geng, Y.,Bush, M.,Mosyak, L.,Wang, F.,Fan, Q.R. (deposition date: 2013-09-16, release date: 2013-12-11, Last modification date: 2023-09-20)
Primary citation	Geng, Y.,Bush, M.,Mosyak, L.,Wang, F.,Fan, Q.R. Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504:254-259, 2013 Cited by PubMed: 24305054 DOI: 10.1038/nature12725 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation