4MRM
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist phaclofen
Summary for 4MRM
Entry DOI | 10.2210/pdb4mrm/pdb |
Related | 4MQE 4MQF 4MR7 4MR8 4MR9 4MS1 4MS3 4MS4 |
Descriptor | Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, beta-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | heterodimeric protein complex, venus flytrap module, neurotransmitter receptor, signaling protein-antagonist complex, signaling protein/antagonist |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 98417.06 |
Authors | Geng, Y.,Bush, M.,Mosyak, L.,Wang, F.,Fan, Q.R. (deposition date: 2013-09-17, release date: 2013-12-11, Last modification date: 2023-09-20) |
Primary citation | Geng, Y.,Bush, M.,Mosyak, L.,Wang, F.,Fan, Q.R. Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504:254-259, 2013 Cited by PubMed: 24305054DOI: 10.1038/nature12725 PDB entries with the same primary citation |
Experimental method |
Structure validation
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