4PB0
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![BU of 4pb0 by Molmil](/molmil-images/mine/4pb0) | Structure of the Fab fragment of the anti-Francisella tularensis GroEL antibody Ab53 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ab53 heavy chain, Ab53 light chain, ... | Authors: | Lu, Z, Rynkiewicz, M.J, Seaton, B.A, Sharon, J. | Deposit date: | 2014-04-10 | Release date: | 2014-07-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | B-Cell Epitopes in GroEL of Francisella tularensis. Plos One, 9, 2014
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4PUB
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![BU of 4pub by Molmil](/molmil-images/mine/4pub) | Crystal structure of Fab DX-2930 | Descriptor: | CHLORIDE ION, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN | Authors: | Abendroth, J, Edwards, T.E, Nixon, A, Ladner, R. | Deposit date: | 2014-03-12 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
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4QHN
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![BU of 4qhn by Molmil](/molmil-images/mine/4qhn) | I2 (unbound) from CH103 Lineage | Descriptor: | I2 heavy chain, I2 light chain | Authors: | Fera, D, Harrison, S.C. | Deposit date: | 2014-05-28 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proc.Natl.Acad.Sci.USA, 111, 2014
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4R7D
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![BU of 4r7d by Molmil](/molmil-images/mine/4r7d) | Fab Hu 15C1 | Descriptor: | Fab Hu 15C1 Heavy chain, Fab Hu 15C1 Light chain | Authors: | Loyau, J, Didelot, G, Malinge, P, Ravn, U, Magistrelli, G, Depoisier, J.F, Kosco-Vilbois, M, Fischer, N, Thore, S, Rousseau, F. | Deposit date: | 2014-08-27 | Release date: | 2015-07-29 | Last modified: | 2015-08-26 | Method: | X-RAY DIFFRACTION (2.753 Å) | Cite: | Robust Antibody-Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking. J.Mol.Biol., 427, 2015
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4OCY
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![BU of 4ocy by Molmil](/molmil-images/mine/4ocy) | Fab for methotrexate (unbound apo) | Descriptor: | Fab ADD058 Heavy Chain, Fab ADD058 Light Chain | Authors: | Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S. | Deposit date: | 2014-01-09 | Release date: | 2014-07-02 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry, 53, 2014
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4R26
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![BU of 4r26 by Molmil](/molmil-images/mine/4r26) | Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | Descriptor: | GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain | Authors: | Garces, F, Kong, L, Wilson, I.A. | Deposit date: | 2014-08-08 | Release date: | 2014-10-08 | Last modified: | 2017-06-21 | Method: | X-RAY DIFFRACTION (2.4969 Å) | Cite: | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies. Cell(Cambridge,Mass.), 159, 2014
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4QHM
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![BU of 4qhm by Molmil](/molmil-images/mine/4qhm) | I3.1 (unbound) from CH103 Lineage | Descriptor: | I2 light chain, I3 heavy chain | Authors: | Fera, D, Harrison, S.C. | Deposit date: | 2014-05-28 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proc.Natl.Acad.Sci.USA, 111, 2014
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4TQE
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![BU of 4tqe by Molmil](/molmil-images/mine/4tqe) | |
4TPR
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![BU of 4tpr by Molmil](/molmil-images/mine/4tpr) | Structure of Tau5 antibody Fab fragment | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol, CHLORIDE ION, ... | Authors: | Cehlar, O, Skrabana, R, Novak, M. | Deposit date: | 2014-06-09 | Release date: | 2015-07-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of Tau5 antibody Fab fragment To Be Published
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4ONO
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![BU of 4ono by Molmil](/molmil-images/mine/4ono) | CD1c in complex with PM (phosphomycoketide) | Descriptor: | (4R,8S,16S,20R)-4,8,12,16,20-pentamethylheptacosyl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin/T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric protein, ... | Authors: | Roy, S, Adams, E.J. | Deposit date: | 2014-01-28 | Release date: | 2014-10-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells. Proc.Natl.Acad.Sci.USA, 111, 2014
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4OCX
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![BU of 4ocx by Molmil](/molmil-images/mine/4ocx) | Fab complex with methotrexate | Descriptor: | Fab ADD056 Heavy Chain, Fab ADD056 Light Chain, N-(4-{[(2,4-DIAMINOPTERIDIN-1-IUM-6-YL)METHYL](METHYL)AMINO}BENZOYL)-L-GLUTAMIC ACID | Authors: | Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S. | Deposit date: | 2014-01-09 | Release date: | 2014-07-02 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry, 53, 2014
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6UBI
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![BU of 6ubi by Molmil](/molmil-images/mine/6ubi) | |
6UGU
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![BU of 6ugu by Molmil](/molmil-images/mine/6ugu) | Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a C-centered orthorhombic crystal form, Lot C | Descriptor: | PF06438179 Fab Heavy Chain, PF06438179 Fab Light Chain | Authors: | Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D. | Deposit date: | 2019-09-26 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
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6UC5
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![BU of 6uc5 by Molmil](/molmil-images/mine/6uc5) | Fab397 in complex with NPNA peptide | Descriptor: | Fab397 heavy chain, Fab397 light chain, NPNA peptide | Authors: | Pholcharee, T, Oyen, D, Wilson, I.A. | Deposit date: | 2019-09-13 | Release date: | 2020-01-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein. J.Mol.Biol., 432, 2020
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6UGS
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![BU of 6ugs by Molmil](/molmil-images/mine/6ugs) | Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A | Descriptor: | Infliximab (Remicade) Fab Heavy Chain, Infliximab (Remicade) Fab Light Chain | Authors: | Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H. | Deposit date: | 2019-09-26 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
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6UCE
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6U07
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![BU of 6u07 by Molmil](/molmil-images/mine/6u07) | Computational Stabilization of T Cell Receptor Constant Domains | Descriptor: | MAGNESIUM ION, Stabilized T cell receptor constant domain (Calpha), Stabilized T cell receptor constant domain (Cbeta) | Authors: | Froning, K, Maguire, J, Sereno, A, Huang, F, Chang, S, Weichert, K, Frommelt, A.J, Dong, J, Wu, X, Austin, H, Conner, E.M, Fitchett, J.R, Heng, A.R, Balasubramaniam, D, Hilgers, M.T, Kuhlman, B, Demarest, S.J. | Deposit date: | 2019-08-13 | Release date: | 2020-04-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics. Nat Commun, 11, 2020
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6UCF
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6UGT
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![BU of 6ugt by Molmil](/molmil-images/mine/6ugt) | Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a I-centered orthorhombic crystal form, Lot A | Descriptor: | 1,2-ETHANEDIOL, PF06438179 Fab Heavy Chain, PF06438179 Fab Light Chain | Authors: | Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D. | Deposit date: | 2019-09-26 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
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6UOE
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![BU of 6uoe by Molmil](/molmil-images/mine/6uoe) | |
6V80
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6V7Z
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![BU of 6v7z by Molmil](/molmil-images/mine/6v7z) | Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D22 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | Authors: | Shahine, A, Rossjohn, J. | Deposit date: | 2019-12-10 | Release date: | 2020-09-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response. Nat Cancer, 2020
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6V7Y
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![BU of 6v7y by Molmil](/molmil-images/mine/6v7y) | Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | Authors: | Shahine, A, Rossjohn, J. | Deposit date: | 2019-12-10 | Release date: | 2020-09-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response. Nat Cancer, 2020
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6VPY
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![BU of 6vpy by Molmil](/molmil-images/mine/6vpy) | I33M (I3.2 mutant from CH103 Lineage) | Descriptor: | CHLORIDE ION, GLYCEROL, I33M heavy chain, ... | Authors: | Fera, D, Zhou, J. | Deposit date: | 2020-02-04 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | The Effects of Framework Mutations at the Variable Domain Interface on Antibody Affinity Maturation in an HIV-1 Broadly Neutralizing Antibody Lineage. Front Immunol, 11, 2020
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6UGV
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![BU of 6ugv by Molmil](/molmil-images/mine/6ugv) | Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a I-centered orthorhombic crystal form, Lot C | Descriptor: | 1,2-ETHANEDIOL, Infliximab Fab Heavy Chain, Infliximab Fab Light Chain, ... | Authors: | Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D. | Deposit date: | 2019-09-26 | Release date: | 2019-11-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
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