4R26
Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody
Summary for 4R26
Entry DOI | 10.2210/pdb4r26/pdb |
Descriptor | PGR124-Light Chain, PGT124-Heavy Chain, GLYCEROL, ... (4 entities in total) |
Functional Keywords | immune system, igg fold, antibody, hiv-1 binding |
Biological source | Nomascus leucogenys (Northern white-cheeked gibbon) More |
Cellular location | Secreted : P0DOY3 P0DOX5 |
Total number of polymer chains | 2 |
Total formula weight | 48793.39 |
Authors | Garces, F.,Kong, L.,Wilson, I.A. (deposition date: 2014-08-08, release date: 2014-10-08, Last modification date: 2017-06-21) |
Primary citation | Garces, F.,Sok, D.,Kong, L.,McBride, R.,Kim, H.J.,Saye-Francisco, K.F.,Julien, J.P.,Hua, Y.,Cupo, A.,Moore, J.P.,Paulson, J.C.,Ward, A.B.,Burton, D.R.,Wilson, I.A. Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies. Cell(Cambridge,Mass.), 159:69-79, 2014 Cited by PubMed: 25259921DOI: 10.1016/j.cell.2014.09.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4969 Å) |
Structure validation
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