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6EJW	Tryptophan Repressor TrpR from E.coli wildtype with Indole-3-acetic acid as ligand Descriptor: 1H-INDOL-3-YLACETIC ACID, Trp operon repressor Authors: Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. Deposit date: 2017-09-23 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.99 Å) Cite: A biosensor for the direct visualization of auxin Nature, 2021
6ELG	Tryptophan Repressor TrpR from E.coli variant M42F T44L T81I S88Y with Indole-3-acetonitrile Descriptor: 1H-indol-3-ylacetonitrile, Trp operon repressor Authors: Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. Deposit date: 2017-09-28 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.38 Å) Cite: A biosensor for the direct visualization of auxin Nature, 2021
6EKP	Tryptophan Repressor TrpR from E.coli variant T44L T81M S88Y with Indole-3-acetic acid as ligand Descriptor: 1H-INDOL-3-YLACETIC ACID, 3,6,9,12,15-PENTAOXAHEPTADECANE, Trp operon repressor Authors: Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. Deposit date: 2017-09-26 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.46 Å) Cite: A biosensor for the direct visualization of auxin Nature, 2021
3LO1	Crystal structure of human alpha-defensin 1 (Y16A mutant) Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, AZIDE ION, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3LOE	Crystal structure of human alpha-defensin 1 (F28A mutant) Descriptor: GLYCEROL, Neutrophil defensin 1, SULFATE ION Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3LO4	Crystal structure of human alpha-defensin 1 (R24A mutant) Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
5DVZ	Holo TrpB from Pyrococcus furiosus Descriptor: PHOSPHATE ION, SODIUM ION, Tryptophan synthase beta chain 1 Authors: Buller, A.R, Arnold, F.H. Deposit date: 2015-09-21 Release date: 2016-02-03 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Directed evolution of the tryptophan synthase beta-subunit for stand-alone function recapitulates allosteric activation. Proc.Natl.Acad.Sci.USA, 112, 2015
1C07	STRUCTURE OF THE THIRD EPS15 HOMOLOGY DOMAIN OF HUMAN EPS15 Descriptor: CALCIUM ION, PROTEIN (EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE 15) Authors: Enmon, J.L, De Beer, T, Overduin, M. Deposit date: 1999-07-14 Release date: 2000-07-19 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure of Eps15's third EH domain reveals coincident Phe-Trp and Asn-Pro-Phe binding sites. Biochemistry, 39, 2000
2VB5	Solution structure of W60G mutant of human beta2-microglobulin Descriptor: BETA-2-MICROGLOBULIN Authors: Esposito, G, Corazza, A, Rennella, E, Gumral, D, Mimmi, M.C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M, Bellotti, V. Deposit date: 2007-09-06 Release date: 2007-09-25 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: The Controlling Roles of Trp60 and Trp95 in Beta2-Microglobulin Function, Folding and Amyloid Aggregation Properties. J.Mol.Biol., 378, 2008
6ELB	Tryptophan Repressor TrpR from E.coli variant M42F T44L T81M N87G S88Y with Indole-3-acetic acid as ligand Descriptor: 1H-INDOL-3-YLACETIC ACID, Trp operon repressor Authors: Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. Deposit date: 2017-09-28 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.437 Å) Cite: A biosensor for the direct visualization of auxin Nature, 2021
6ENI	Tryptophan Repressor TrpR from E.coli variant T44L S88Y with Indole-3-acetic acid as ligand Descriptor: 1,2-ETHANEDIOL, 1H-INDOL-3-YLACETIC ACID, Trp operon repressor Authors: Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. Deposit date: 2017-10-04 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.1 Å) Cite: A biosensor for the direct visualization of auxin Nature, 2021
5SX3	Crystal structure of the catalase-peroxidase KatG of B. pseudomaallei at pH 4.5 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Catalase-peroxidase, ... Authors: Loewen, P.C. Deposit date: 2016-08-09 Release date: 2016-08-31 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Roles for Arg426 and Trp111 in the modulation of NADH oxidase activity of the catalase-peroxidase KatG from Burkholderia pseudomallei inferred from pH-induced structural changes. Biochemistry, 45, 2006
6EJZ	Tryptophan Repressor TrpR from E.coli variant S88Y with Indole-3-acetic acid as ligand Descriptor: 1,2-ETHANEDIOL, 1H-INDOL-3-YLACETIC ACID, SULFATE ION, ... Authors: Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. Deposit date: 2017-09-24 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A biosensor for the direct visualization of auxin Nature, 2021
6ELF	Tryptophan Repressor TrpR from E.coli variant M42F T44L T81I S88Y with Indole-3-acetic acid as ligand Descriptor: 1H-INDOL-3-YLACETIC ACID, Trp operon repressor Authors: Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. Deposit date: 2017-09-28 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.832 Å) Cite: A biosensor for the direct visualization of auxin Nature, 2021
6ENN	Tryptophan Repressor TrpR from E.coli variant T44L T81M N87G S88Y with Indole-3-acetic acid as ligand Descriptor: 1H-INDOL-3-YLACETIC ACID, Trp operon repressor Authors: Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. Deposit date: 2017-10-05 Release date: 2019-02-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.17 Å) Cite: A biosensor for the direct visualization of auxin Nature, 2021
1UTD	The structure of the trp RNA-binding attenuation protein (TRAP) bound to a 63-nucleotide RNA molecule containing GAGUUU repeats Descriptor: 5'-R(*GP*UP*UP*UP*GP*AP)-3', TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN Authors: Hopcroft, N.H, Manfredo, A, Wendt, A.L, Brzozowski, A.M, Gollnick, P, Antson, A.A. Deposit date: 2003-12-08 Release date: 2004-01-15 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The Interaction of RNA with Trap: The Role of Triplet Repeats and Separating Spacer Nucleotides J.Mol.Biol., 338, 2004
7NGE	Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the closed conformation Descriptor: CHLORIDE ION, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... Authors: Mirgaux, M, Wouters, J. Deposit date: 2021-02-09 Release date: 2021-12-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site. Int J Tryptophan Res, 14, 2021
1I7S	ANTHRANILATE SYNTHASE FROM SERRATIA MARCESCENS IN COMPLEX WITH ITS END PRODUCT INHIBITOR L-TRYPTOPHAN Descriptor: ANTHRANILATE SYNTHASE, TRPG, TRYPTOPHAN Authors: Spraggon, G, Kim, C, Nguyen-Huu, X, Yee, M.-C, Yanofsky, C, Mills, S.E. Deposit date: 2001-03-10 Release date: 2001-05-16 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan. Proc.Natl.Acad.Sci.USA, 98, 2001
5OEO	Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant Descriptor: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5 Authors: Vuister, G.W, Bokhovchuk, F.M, Bate, N, Kovalevskaya, N, Goult, B.T, Spronk, C.A.E.M. Deposit date: 2017-07-09 Release date: 2018-04-25 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The Structural Basis of Calcium-Dependent Inactivation of the Transient Receptor Potential Vanilloid 5 Channel. Biochemistry, 57, 2018
8I2J	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface Descriptor: 1-(4-methoxyphenyl)ethanone, SULFATE ION, TRYPTOPHANYL-5'AMP, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.65 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I27	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface Descriptor: 1,2-ETHANEDIOL, 4-methoxybenzenecarbonitrile, SULFATE ION, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I2A	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface Descriptor: 1,2-ETHANEDIOL, 5-METHOXYBENZIMIDAZOLE, SULFATE ION, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.35 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I2M	The crystal structure of homodimeric E. coli tryptophanyl-tRNA synthetase bound with niraparib at one of its two active sites Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, SULFATE ION, TRYPTOPHANYL-5'AMP, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I2C	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface Descriptor: 1,2-ETHANEDIOL, 4-methoxyaniline, SULFATE ION, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.07 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I1Z	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment Descriptor: 1-(2,3-dihydro-1-benzofuran-5-yl)ethanone, SULFATE ION, TRYPTOPHANYL-5'AMP, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-13 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023

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