6LXP
 
 | | TvCyP2 in apo form 2 | | Descriptor: | Peptidyl-prolyl cis-trans isomerase | | Authors: | Aryal, S, Chen, C, Hsu, C.H. | | Deposit date: | 2020-02-11 | | Release date: | 2020-09-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | N-Terminal Segment of TvCyP2 Cyclophilin fromTrichomonas vaginalisIs Involved in Self-Association, Membrane Interaction, and Subcellular Localization.
Biomolecules, 10, 2020
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2Y4O
 | | Crystal Structure of PaaK2 in complex with phenylacetyl adenylate | | Descriptor: | 5'-O-[HYDROXY(PHENYLACETYL)PHOSPHORYL]ADENOSINE, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Law, A, Boulanger, M.J. | | Deposit date: | 2011-01-07 | | Release date: | 2011-03-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Defining a Structural and Kinetic Rationale for Paralogous Copies of Phenylacetate-Coa Ligases from the Cystic Fibrosis Pathogen Burkholderia Cenocepacia J2315.
J.Biol.Chem., 286, 2011
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2Y4N
 | | PaaK1 in complex with phenylacetyl adenylate | | Descriptor: | 2-PHENYLACETIC ACID, 5'-O-[HYDROXY(PHENYLACETYL)PHOSPHORYL]ADENOSINE, BETA-MERCAPTOETHANOL, ... | | Authors: | Law, A, Boulanger, M.J. | | Deposit date: | 2011-01-07 | | Release date: | 2011-03-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Defining a Structural and Kinetic Rationale for Paralogous Copies of Phenylacetate-Coa Ligases from the Cystic Fibrosis Pathogen Burkholderia Cenocepacia J2315.
J.Biol.Chem., 286, 2011
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4XL1
 | | Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Luca, V.C, Jude, K.M, Garcia, K.C. | | Deposit date: | 2015-01-13 | | Release date: | 2015-03-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Science, 347, 2015
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4XLW
 | | Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Delta-like protein, ... | | Authors: | Luca, V.C, Jude, K.M, Garcia, K.C. | | Deposit date: | 2015-01-13 | | Release date: | 2015-03-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.39 Å) | | Cite: | Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Science, 347, 2015
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6KHI
 | | Supercomplex for cylic electron transport in cyanobacteria | | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | Authors: | Pan, X, Cao, D, Xie, F, Zhang, X, Li, M. | | Deposit date: | 2019-07-15 | | Release date: | 2020-02-12 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for electron transport mechanism of complex I-like photosynthetic NAD(P)H dehydrogenase.
Nat Commun, 11, 2020
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6L7O
 | | cryo-EM structure of cyanobacteria Fd-NDH-1L complex | | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ... | | Authors: | Zhang, C, Shuai, J, Wu, J, Lei, M. | | Deposit date: | 2019-11-02 | | Release date: | 2020-02-19 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into NDH-1 mediated cyclic electron transfer.
Nat Commun, 11, 2020
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4D0E
 | | Human Notch1 EGF domains 11-13 mutant GlcNAc-fucose disaccharide modified at T466 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | Authors: | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | Deposit date: | 2014-04-25 | | Release date: | 2014-05-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CUD
 | | Human Notch1 EGF domains 11-13 mutant fucosylated at T466 | | Descriptor: | CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, alpha-L-fucopyranose | | Authors: | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | Deposit date: | 2014-03-18 | | Release date: | 2014-05-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CUF
 | | Human Notch1 EGF domains 11-13 mutant T466S | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | Authors: | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | Deposit date: | 2014-03-18 | | Release date: | 2014-05-14 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4D0F
 | | Human Notch1 EGF domains 11-13 mutant T466A | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | Authors: | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | Deposit date: | 2014-04-25 | | Release date: | 2014-05-21 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CUE
 | | Human Notch1 EGF domains 11-13 mutant T466V | | Descriptor: | CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | Authors: | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | Deposit date: | 2014-03-18 | | Release date: | 2014-05-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1FV3
 | | THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH AN ANALOGUE OF ITS GANGLIOSIDE RECEPTOR GT1B | | Descriptor: | ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ... | | Authors: | Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W. | | Deposit date: | 2000-09-18 | | Release date: | 2001-09-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin.
J.Biol.Chem., 276, 2001
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1FV2
 | | The Hc fragment of tetanus toxin complexed with an analogue of its ganglioside receptor GT1B | | Descriptor: | ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ... | | Authors: | Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W. | | Deposit date: | 2000-09-18 | | Release date: | 2001-09-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin.
J.Biol.Chem., 276, 2001
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2IGZ
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2IH0
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5FM9
 | | human Notch 1, EGF 4-7 | | Descriptor: | CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | Authors: | Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C. | | Deposit date: | 2015-11-02 | | Release date: | 2016-04-20 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
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5FMA
 | | human Notch 1, EGF 4-7 | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C. | | Deposit date: | 2015-11-02 | | Release date: | 2016-04-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Structure, 24, 2016
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4U8U
 | | The Crystallographic structure of the giant hemoglobin from Glossoscolex paulistus at 3.2 A resolution. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYANIDE ION, ... | | Authors: | Bachega, J.F.R, Maluf, F.V, Andi, B, D'Muniz Pereira, H, Carazzollea, M.F, Orville, A, Tabak, M, Garratt, R.C, Horjales, E. | | Deposit date: | 2014-08-04 | | Release date: | 2015-06-10 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The structure of the giant haemoglobin from Glossoscolex paulistus.
Acta Crystallogr.,Sect.D, 71, 2015
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4V93
 | | Fitted coordinates for Lumbricus terrestris hemoglobin cryo-EM complex (EMD-2627) | | Descriptor: | EXTRACELLULAR GLOBIN-2, EXTRACELLULAR GLOBIN-3, EXTRACELLULAR GLOBIN-4, ... | | Authors: | Chen, W.T, Chen, Y.C, Liou, H.H, Chao, C.Y. | | Deposit date: | 2014-04-16 | | Release date: | 2014-07-09 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (8.1 Å) | | Cite: | Structural Basis for Cooperative Oxygen Binding and Bracelet-Assisted Assembly of Lumbricus Terrestris Hemoglobin
To be Published
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7O5B
 | | Cryo-EM structure of a Bacillus subtilis MifM-stalled ribosome-nascent chain complex with (p)ppGpp-SRP bound | | Descriptor: | 16S rRNA (1533-MER), 23S rRNA (2887-MER), 30S ribosomal protein S10, ... | | Authors: | Kratzat, H, Czech, L, Berninghausen, O, Bange, G, Beckmann, R. | | Deposit date: | 2021-04-08 | | Release date: | 2022-02-02 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp.
Nat Commun, 13, 2022
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9GH3
 | | pleckstrin homology domain interacting protein with crystallization epitope mutations L1408N:R1409E | | Descriptor: | 1,2-ETHANEDIOL, PH-interacting protein | | Authors: | Fairhead, M, Strain-Damerell, C, Ye, M, Mackinnon, S.R, Pinkas, D, MacLean, E.M, Koekemoer, L, Damerell, D, Krojer, T, Arrowsmith, C.H, Edwards, A, Yue, W, Burgess-Brown, N, Marsden, B, von Delft, F, Structural Genomics Consortium (SGC) | | Deposit date: | 2024-08-14 | | Release date: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (1.19 Å) | | Cite: | A fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants
To Be Published
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6UQK
 | | Cryo-EM structure of type 3 IP3 receptor revealing presence of a self-binding peptide | | Descriptor: | ZINC ION, inositol 1,4,5-triphosphate receptor, type 3 | | Authors: | Azumaya, C.M, Linton, E.A, Risener, C.J, Nakagawa, T, Karakas, E. | | Deposit date: | 2019-10-20 | | Release date: | 2020-01-15 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.77 Å) | | Cite: | Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist.
J.Biol.Chem., 295, 2020
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5K8D
 | | Crystal structure of rFVIIIFc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ... | | Authors: | Leksa, N, Quan, C. | | Deposit date: | 2016-05-29 | | Release date: | 2017-06-14 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (4.19 Å) | | Cite: | The structural basis for the functional comparability of factor VIII and the long-acting variant recombinant factor VIII Fc fusion protein.
J. Thromb. Haemost., 15, 2017
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4OD2
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