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6UQK

Cryo-EM structure of type 3 IP3 receptor revealing presence of a self-binding peptide

Summary for 6UQK
Entry DOI10.2210/pdb6uqk/pdb
EMDB information20849
Descriptorinositol 1,4,5-triphosphate receptor, type 3, ZINC ION (2 entities in total)
Functional Keywordsinositol trisphosphate receptor, insp3r, ip3r, cryoelectron microscopy, ion channel, calcium channel, isothermal titration calorimetry, self binding peptide, transport protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight1114599.26
Authors
Azumaya, C.M.,Linton, E.A.,Risener, C.J.,Nakagawa, T.,Karakas, E. (deposition date: 2019-10-20, release date: 2020-01-15, Last modification date: 2024-03-20)
Primary citationAzumaya, C.M.,Linton, E.A.,Risener, C.J.,Nakagawa, T.,Karakas, E.
Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist.
J.Biol.Chem., 295:1743-1753, 2020
Cited by
PubMed: 31915246
DOI: 10.1074/jbc.RA119.011570
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.77 Å)
Structure validation

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