PDB: 26577 resultsInfo pagesStatus searchChemie searchBIRD

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7NXV	Crystal structure of the complex of DNase I/G-actin/PPP1R15A_582-621 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... Authors: Yan, Y, Ron, D. Deposit date: 2021-03-19 Release date: 2021-09-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
7NZM	Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... Authors: Yan, Y, Hardwick, S, Ron, D. Deposit date: 2021-03-24 Release date: 2021-09-29 Last modified: 2021-10-20 Method: ELECTRON MICROSCOPY (3.96 Å) Cite: Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
7NYC	cryoEM structure of 3C9-sMAC Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Menny, A, Couves, E.C, Bubeck, D. Deposit date: 2021-03-22 Release date: 2021-10-06 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Structural basis of soluble membrane attack complex packaging for clearance. Nat Commun, 12, 2021
7O3E	Murine supercomplex CIII2CIV in the intermediate locked conformation Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... Authors: Vercellino, I, Sazanov, L.A. Deposit date: 2021-04-01 Release date: 2021-10-13 Last modified: 2021-10-27 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV. Nature, 598, 2021
7NRO	Crystal structure of AlkB in complex with manganese and N-(4-((6-((carboxymethyl)carbamoyl)-5-hydroxypyridin-2-yl)amino)phenyl)-N-oxohydroxylammonium Descriptor: 2-[[6-[(4-nitrophenyl)amino]-3-oxidanyl-pyridin-2-yl]carbonylamino]ethanoic acid, Alpha-ketoglutarate-dependent dioxygenase AlkB, MANGANESE (II) ION Authors: Shishodia, S, Maheswaran, P, Leissing, T, Aik, W.S, McDonough, M.A, Schofield, C.J. Deposit date: 2021-03-04 Release date: 2021-10-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors. J.Med.Chem., 64, 2021
7O3C	Murine supercomplex CIII2CIV in the mature unlocked conformation Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... Authors: Vercellino, I, Sazanov, L.A. Deposit date: 2021-04-01 Release date: 2021-10-13 Last modified: 2021-10-27 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV. Nature, 598, 2021
7O37	Murine supercomplex CIII2CIV in the assembled locked conformation Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... Authors: Vercellino, I, Sazanov, L.A. Deposit date: 2021-04-01 Release date: 2021-10-13 Last modified: 2021-10-27 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV. Nature, 598, 2021
7O3H	Murine CIII2 focus-refined from supercomplex CICIII2 Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... Authors: Vercellino, I, Sazanov, L.A. Deposit date: 2021-04-01 Release date: 2021-10-13 Last modified: 2021-10-27 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV. Nature, 598, 2021
6PB1	Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35 Descriptor: CHOLESTEROL, Corticotropin-releasing factor receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. Deposit date: 2019-06-12 Release date: 2020-02-12 Last modified: 2020-02-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
6PG4	WDR5delta32 bound to (2-methyl-1H-imidazol-4-yl)methanol Descriptor: (2-methyl-1H-imidazol-4-yl)methanol, SULFATE ION, WD repeat-containing protein 5 Authors: Dennis, M.L, Peat, T.S. Deposit date: 2019-06-24 Release date: 2019-12-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
6PG9	WDR5delta23 bound to N-(4-(5-(hydroxymethyl)-1H-imidazol-2-yl)butyl)benzamide Descriptor: N-{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}benzamide, WD repeat-containing protein 5 Authors: Dennis, M.L, Peat, T.S. Deposit date: 2019-06-24 Release date: 2019-12-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
6PGA	WDR5delta32 bound to methyl (4-(4-(hydroxymethyl)-1H-imidazol-2-yl)butyl)carbamate Descriptor: SULFATE ION, WD repeat-containing protein 5, methyl {4-[5-(hydroxymethyl)-1H-imidazol-2-yl]butyl}carbamate Authors: Dennis, M.L, Peat, T.S. Deposit date: 2019-06-24 Release date: 2019-12-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
7O71	Cryo-EM structure of a respiratory complex I Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... Authors: Parey, K, Vonck, J. Deposit date: 2021-04-12 Release date: 2021-11-10 Last modified: 2021-12-01 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Sci Adv, 7, 2021
7NXF	Structure of the fungal plasma membrane proton pump Pma1 in its auto-inhibited state - monomer unit Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... Authors: Heit, S, Geurts, M.M.G, Murphy, B.J, Corey, R, Mills, D.J, Kuehlbrandt, W, Bublitz, M. Deposit date: 2021-03-18 Release date: 2021-11-17 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state. Sci Adv, 7, 2021
7NY1	Structure of the fungal plasma membrane proton pump Pma1 in its auto-inhibited state - hexameric assembly Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... Authors: Heit, S, Geurts, M.M.G, Murphy, B.J, Corey, R, Mills, D.J, Kuehlbrandt, W, Bublitz, M. Deposit date: 2021-03-19 Release date: 2021-11-17 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state. Sci Adv, 7, 2021
7NYD	cryoEM structure of 2C9-sMAC Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Menny, A, Couves, E.C, Bubeck, D. Deposit date: 2021-03-22 Release date: 2021-10-06 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.27 Å) Cite: Structural basis of soluble membrane attack complex packaging for clearance. Nat Commun, 12, 2021
7O6Y	Cryo-EM structure of respiratory complex I under turnover Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... Authors: Parey, K, Vonck, J. Deposit date: 2021-04-12 Release date: 2021-11-10 Last modified: 2021-12-01 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Sci Adv, 7, 2021
6PWW	Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome Descriptor: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. Deposit date: 2019-07-23 Release date: 2019-12-18 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
6Q6V	Crystal structure (trigonal form) of C36S mutant of thioredoxin h1 from Chlamydomonas reinhardtii Descriptor: DI(HYDROXYETHYL)ETHER, Thioredoxin H-type Authors: Fermani, S, Zaffagnini, M, Lemaire, S.D. Deposit date: 2018-12-11 Release date: 2019-01-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.22 Å) Cite: Structural and Biochemical Insights into the Reactivity of Thioredoxin h1 fromChlamydomonas reinhardtii. Antioxidants (Basel), 8, 2019
6KXR	Crystal structure of wild type Alp1U from the biosynthesis of kinamycins Descriptor: D-MALATE, Putative hydrolase Authors: Zhang, L, Yingli, Z, De, B.C, Zhang, C. Deposit date: 2019-09-12 Release date: 2020-09-16 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.45073676 Å) Cite: Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U. J.Biol.Chem., 295, 2020
6KXH	Alp1U_Y247F mutant in complex with Fluostatin C Descriptor: D-MALATE, Fluostatin C, Putative hydrolase, ... Authors: Zhang, L, Yingli, Z, De, B.C, Zhang, C. Deposit date: 2019-09-11 Release date: 2020-09-16 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.78039551 Å) Cite: Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U. J.Biol.Chem., 295, 2020
2VOV	An oxidized tryptophan facilitates copper-binding in Methylococcus capsulatus secreted protein MopE. The structure of wild-type MopE to 1.35AA Descriptor: CALCIUM ION, COPPER (II) ION, SURFACE-ASSOCIATED PROTEIN Authors: Helland, R, Fjellbirkeland, A, Karlsen, O.A, Ve, T, Lillehaug, J.R, Jensen, H.B. Deposit date: 2008-02-22 Release date: 2008-03-18 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.35 Å) Cite: An Oxidized Tryptophan Facilitates Copper Binding in Methylococcus Capsulatus-Secreted Protein Mope. J.Biol.Chem., 283, 2008
8K33	SOD1 and Nanobody1 complex Descriptor: NB1, Superoxide dismutase [Cu-Zn], ZINC ION Authors: Cheng, S. Deposit date: 2023-07-14 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (2.13 Å) Cite: SOD1 and Nanobody1 complex To Be Published
8K3A	SOD1 and Nanobody2 complex Descriptor: NB2, Superoxide dismutase [Cu-Zn], ZINC ION Authors: Cheng, S. Deposit date: 2023-07-14 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (2.74 Å) Cite: SOD1 and Nanobody1 complex To Be Published
8K3L	SOD1 and Nanobody3 complex Descriptor: COPPER (II) ION, NB3, Superoxide dismutase [Cu-Zn], ... Authors: Cheng, S, Liu, R, Ding, Y. Deposit date: 2023-07-16 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (2.3 Å) Cite: SOD1 and Nanobody1 complex To Be Published

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