7NYD

cryoEM structure of 2C9-sMAC

This is a non-PDB format compatible entry.

Summary for 7NYD

• Entry DOI: 10.2210/pdb7nyd/pdb
• Related: 7NYC
• EMDB information: 12646 12647 12648 12649 12650 12651
• Descriptor: Complement component C8 beta chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose, ... (14 entities in total)
• Functional Keywords: complement, macpf, membrane attack complex, cdc, pore forming, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 649729.38

Authors

Menny, A.,Couves, E.C.,Bubeck, D. (deposition date: 2021-03-22, release date: 2021-10-06, Last modification date: 2021-11-17)

• Primary citation: Menny, A.,Lukassen, M.V.,Couves, E.C.,Franc, V.,Heck, A.J.R.,Bubeck, D.; Structural basis of soluble membrane attack complex packaging for clearance.; Nat Commun, 12:6086-6086, 2021; PubMed: 34667172; DOI: 10.1038/s41467-021-26366-w

Experimental method

ELECTRON MICROSCOPY (3.3 Å)