4UNS
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![BU of 4uns by Molmil](/molmil-images/mine/4uns) | Mtb TMK in complex with compound 40 | Descriptor: | N-[4-(3-CYANO-7-ETHYL-5-METHYL-2-OXO-1H-1,6-NAPHTHYRIDIN-4-YL)PHENYL]METHANESULFONAMIDE, SODIUM ION, THYMIDYLATE KINASE | Authors: | Read, J.A, Hussein, S, Gingell, H, Tucker, J. | Deposit date: | 2014-05-30 | Release date: | 2015-06-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structure Guided Lead Generation for M. Tuberculosis Thymidylate Kinase (Mtb Tmk): Discovery of 3-Cyanopyridone and 1,6-Naphthyridin-2-One as Potent Inhibitors. J.Med.Chem., 58, 2015
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2HED
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![BU of 2hed by Molmil](/molmil-images/mine/2hed) | CONTRIBUTION OF WATER MOLECULES IN THE INTERIOR OF A PROTEIN TO THE CONFORMATIONAL STABILITY | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Funahashi, J, Yamagata, Y, Fujii, S, Yutani, K. | Deposit date: | 1997-09-16 | Release date: | 1998-01-14 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of water molecules in the interior of a protein to the conformational stability. J.Mol.Biol., 274, 1997
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6K96
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![BU of 6k96 by Molmil](/molmil-images/mine/6k96) | Crystal structure of Ari2 | Descriptor: | Five-membered-cyclitol-phosphate synthase, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Miyanaga, A, Tsunoda, T, Kudo, F, Eguchi, T. | Deposit date: | 2019-06-14 | Release date: | 2019-12-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Stereochemistry in the Reaction of themyo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis. Biochemistry, 58, 2019
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3GOX
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![BU of 3gox by Molmil](/molmil-images/mine/3gox) | Crystal structure of the beta-beta-alpha-Me type II restriction endonuclease Hpy99I in the absence of EDTA | Descriptor: | 5'-(*DCP*DTP*DCP*DGP*DAP*DCP*DGP*DTP*DAP*DGP*DA)-3', 5'-(*DTP*DAP*DCP*DGP*DTP*DCP*DGP*DAP*DGP*DTP*DC)-3', PENTAETHYLENE GLYCOL, ... | Authors: | Sokolowska, M, Czapinska, H, Bochtler, M. | Deposit date: | 2009-03-20 | Release date: | 2009-04-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA. Nucleic Acids Res., 37, 2009
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6KCB
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![BU of 6kcb by Molmil](/molmil-images/mine/6kcb) | |
4TUS
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![BU of 4tus by Molmil](/molmil-images/mine/4tus) | |
4TUQ
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![BU of 4tuq by Molmil](/molmil-images/mine/4tuq) | Human DNA polymerase beta inserting dCMPNPP opposite GG template (GG0b). | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*AP*TP*GP*GP*GP*C)-3'), ... | Authors: | Koag, M.C, Lee, S. | Deposit date: | 2014-06-24 | Release date: | 2014-10-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.367 Å) | Cite: | Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta. J.Biol.Chem., 289, 2014
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4TXO
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![BU of 4txo by Molmil](/molmil-images/mine/4txo) | Crystal structure of the mixed disulfide complex of thioredoxin-like TlpAs(C110S) and copper chaperone ScoIs(C74S) | Descriptor: | Blr1131 protein, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | Authors: | Scharer, M.A, Abicht, H.K, Glockshuber, R, Hennecke, H. | Deposit date: | 2014-07-04 | Release date: | 2014-10-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | How Periplasmic Thioredoxin TlpA Reduces Bacterial Copper Chaperone ScoI and Cytochrome Oxidase Subunit II (CoxB) Prior to Metallation. J.Biol.Chem., 289, 2014
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4H8R
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![BU of 4h8r by Molmil](/molmil-images/mine/4h8r) | Imipenem complex of GES-5 carbapenemase | Descriptor: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Extended-spectrum beta-lactamase GES-5, IODIDE ION, ... | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2012-09-23 | Release date: | 2013-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural basis for progression toward the carbapenemase activity in the GES family of beta-lactamases. J.Am.Chem.Soc., 134, 2012
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1XSL
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![BU of 1xsl by Molmil](/molmil-images/mine/1xsl) | Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap | Descriptor: | 5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*CP*CP*G)-3', ... | Authors: | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Kunkel, T.A, Pedersen, L.C. | Deposit date: | 2004-10-19 | Release date: | 2005-01-18 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A closed conformation for the Pol lambda catalytic cycle. Nat.Struct.Mol.Biol., 12, 2005
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3HB7
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![BU of 3hb7 by Molmil](/molmil-images/mine/3hb7) | The Crystal Structure of an Isochorismatase-like Hydrolase from Alkaliphilus metalliredigens to 2.3A | Descriptor: | AMMONIUM ION, Isochorismatase hydrolase, SODIUM ION | Authors: | Stein, A.J, Xu, X, Cui, H, Ng, J, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-05-04 | Release date: | 2009-07-07 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Crystal Structure of an Isochorismatase-like Hydrolase from Alkaliphilus metalliredigens to 2.3A To be Published
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6LZ2
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![BU of 6lz2 by Molmil](/molmil-images/mine/6lz2) | Crystal structure of a thermostable green fluorescent protein (TGP) with a synthetic nanobody (Sb44) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ... | Authors: | Cai, H, Yao, H, Li, T, Hutter, C, Tang, Y, Li, Y, Seeger, M, Li, D. | Deposit date: | 2020-02-17 | Release date: | 2020-12-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | An improved fluorescent tag and its nanobodies for membrane protein expression, stability assay, and purification. Commun Biol, 3, 2020
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6J6O
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![BU of 6j6o by Molmil](/molmil-images/mine/6j6o) | Crystal structure of diamondback moth ryanodine receptor phosphorylation domain(2836-3050) | Descriptor: | CHLORIDE ION, GLYCEROL, Ryanodine receptor, ... | Authors: | Xu, T, Lin, L, Yuchi, Z. | Deposit date: | 2019-01-15 | Release date: | 2019-09-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.848 Å) | Cite: | Crystal structure of diamondback moth ryanodine receptor Repeat34 domain reveals insect-specific phosphorylation sites. Bmc Biol., 17, 2019
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1YQ2
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![BU of 1yq2 by Molmil](/molmil-images/mine/1yq2) | beta-galactosidase from Arthrobacter sp. C2-2 (isoenzyme C2-2-1) | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Skalova, T, Dohnalek, J, Spiwok, V, Lipovova, P, Vondrackova, E, Petrokova, H, Strnad, H, Kralova, B, Hasek, J. | Deposit date: | 2005-02-01 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cold-active beta-Galactosidase from Arthrobacter sp. C2-2 Forms Compact 660kDa Hexamers: Crystal Structure at 1.9A Resolution J.Mol.Biol., 353, 2005
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2HB6
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![BU of 2hb6 by Molmil](/molmil-images/mine/2hb6) | Structure of Caenorhabditis elegans leucine aminopeptidase (LAP1) | Descriptor: | GLYCEROL, Leucine aminopeptidase 1, SODIUM ION, ... | Authors: | Patskovsky, Y, Zhan, C, Wengerter, B.C, Ramagopal, U, Milstein, S, Vidal, M, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-06-13 | Release date: | 2006-08-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Caenorhabditis Elegans Leucine Aminopeptidase To be Published
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4GU1
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![BU of 4gu1 by Molmil](/molmil-images/mine/4gu1) | Crystal structure of LSD2 | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ... | Authors: | Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. | Deposit date: | 2012-08-29 | Release date: | 2013-01-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.939 Å) | Cite: | LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013
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4HES
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![BU of 4hes by Molmil](/molmil-images/mine/4hes) | Structure of a Beta-Lactamase Class A-like Protein from Veillonella parvula. | Descriptor: | Beta-lactamase class A-like protein, FORMIC ACID, GLYCEROL, ... | Authors: | Cuff, M.E, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-10-04 | Release date: | 2012-10-17 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a Beta-Lactamase Class A-like Protein from Veillonella parvula. TO BE PUBLISHED
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4E1J
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![BU of 4e1j by Molmil](/molmil-images/mine/4e1j) | Crystal structure of glycerol kinase in complex with glycerol from Sinorhizobium meliloti 1021 | Descriptor: | CHLORIDE ION, GLYCEROL, Glycerol kinase, ... | Authors: | Agarwal, R, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Siedel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-03-06 | Release date: | 2012-03-21 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Crystal structure of glycerol kinase in complex with glycerol from Sinorhizobium meliloti 1021 To be Published
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2GC4
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![BU of 2gc4 by Molmil](/molmil-images/mine/2gc4) | Structural comparison of the oxidized ternary electron transfer complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from Paracoccus denitrificans with the substrate-reduced, copper free complex at 1.9 A resolution. | Descriptor: | Amicyanin, COPPER (II) ION, Cytochrome c-L, ... | Authors: | Chen, Z, Durley, R, Davidson, V.L, Mathews, F.S. | Deposit date: | 2006-03-13 | Release date: | 2006-11-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural comparison of the oxidized ternary electron transfer complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from Paracoccus denitrificans with the substrate-reduced, copper free complex at 1.9 A resolution. To be Published
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6K27
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![BU of 6k27 by Molmil](/molmil-images/mine/6k27) | Pyrophosphatase with PPi from Acinetobacter baumannii | Descriptor: | DIPHOSPHATE, Inorganic pyrophosphatase, MAGNESIUM ION | Authors: | Su, J. | Deposit date: | 2019-05-13 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal Structures of Pyrophosphatase from Acinetobacter baumannii: Snapshots of Pyrophosphate Binding and Identification of a Phosphorylated Enzyme Intermediate. Int J Mol Sci, 20, 2019
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4CH8
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![BU of 4ch8 by Molmil](/molmil-images/mine/4ch8) | High-salt crystal structure of a thrombin-GpIbalpha peptide complex | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | Authors: | Lechtenberg, B.C, Freund, S.M.V, Huntington, J.A. | Deposit date: | 2013-11-29 | Release date: | 2013-12-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Gpibalpha Interacts Exclusively with Exosite II of Thrombin J.Mol.Biol., 426, 2014
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4CSH
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![BU of 4csh by Molmil](/molmil-images/mine/4csh) | Native structure of the lytic CHAPK domain of the endolysin LysK from Staphylococcus aureus bacteriophage K | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | Authors: | Sanz-Gaitero, M, Keary, R, Garcia-Doval, C, Coffey, A, van Raaij, M.J. | Deposit date: | 2014-03-07 | Release date: | 2014-08-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal structure of the lytic CHAP(K) domain of the endolysin LysK from Staphylococcus aureus bacteriophage K. Virol. J., 11, 2014
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1IVF
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![BU of 1ivf by Molmil](/molmil-images/mine/1ivf) | STRUCTURES OF AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Jedrzejas, M.J, Luo, M. | Deposit date: | 1994-12-12 | Release date: | 1995-03-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of aromatic inhibitors of influenza virus neuraminidase. Biochemistry, 34, 1995
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4HFP
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![BU of 4hfp by Molmil](/molmil-images/mine/4hfp) | Structure of thrombin mutant S195a bound to the active site inhibitor argatroban | Descriptor: | (2R,4R)-4-methyl-1-(N~2~-{[(3S)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}-L-arginyl)piperidine-2-carboxylic acid, Prothrombin, SODIUM ION | Authors: | Pozzi, N, Chen, Z, Zapata, F, Lin, W, Barranco-Medina, S, Pelc, L.A, Di Cera, E. | Deposit date: | 2012-10-05 | Release date: | 2013-03-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Autoactivation of thrombin precursors. J.Biol.Chem., 288, 2013
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1U8R
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![BU of 1u8r by Molmil](/molmil-images/mine/1u8r) | Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions | Descriptor: | COBALT (II) ION, Iron-dependent repressor ideR, SODIUM ION, ... | Authors: | Wisedchaisri, G, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2004-08-06 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions. J.Mol.Biol., 342, 2004
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