6J6O

Crystal structure of diamondback moth ryanodine receptor phosphorylation domain(2836-3050)

Summary for 6J6O

• Entry DOI: 10.2210/pdb6j6o/pdb
• Descriptor: Ryanodine receptor, SODIUM ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: diamondback moth, ryanodine receptor, phosphorylation domain, transport protein, membrane protein, metal transport
• Biological source: Plutella xylostella (Diamondback moth)
• Total number of polymer chains: 1
• Total formula weight: 25598.24

Authors

Xu, T.,Lin, L.,Yuchi, Z. (deposition date: 2019-01-15, release date: 2019-09-04, Last modification date: 2023-11-22)

Primary citation

Xu, T.,Yuchi, Z.
Crystal structure of diamondback moth ryanodine receptor Repeat34 domain reveals insect-specific phosphorylation sites.
Bmc Biol., 17:77-77, 2019

PubMed Abstract: Ryanodine receptor (RyR), a calcium-release channel located in the sarcoplasmic reticulum membrane of muscles, is the target of insecticides used against a wide range of agricultural pests. Mammalian RyRs have been shown to be under the regulatory control of several kinases and phosphatases, but little is known about the regulation of insect RyRs by phosphorylation.

PubMed: 31597572
DOI: 10.1186/s12915-019-0698-5

Experimental method

X-RAY DIFFRACTION (1.848 Å)