7DC8
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![BU of 7dc8 by Molmil](/molmil-images/mine/7dc8) | Crystal structure of Switch Ab Fab and hIL6R in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Interleukin-6 receptor subunit alpha, SULFATE ION, ... | Authors: | Kadono, S, Fukami, T.A, Kawauchi, H, Torizawa, T, Mimoto, F. | Deposit date: | 2020-10-23 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.757 Å) | Cite: | Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment. Cell Rep, 33, 2020
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7DC7
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![BU of 7dc7 by Molmil](/molmil-images/mine/7dc7) | Crystal structure of D12 Fab-ATP complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, D12 Fab heavy chain, D12 Fab light chain | Authors: | Kawauchi, H, Fukami, T.A, Tatsumi, K, Torizawa, T, Mimoto, F. | Deposit date: | 2020-10-23 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment. Cell Rep, 33, 2020
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3TJE
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![BU of 3tje by Molmil](/molmil-images/mine/3tje) | Crystal structure of Fas receptor extracellular domain in complex with Fab E09 | Descriptor: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | Authors: | Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G. | Deposit date: | 2011-08-24 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency. Cell Death Differ., 19, 2012
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4JDT
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![BU of 4jdt by Molmil](/molmil-images/mine/4jdt) | Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | Authors: | Scharf, L, Diskin, R, Bjorkman, P.J. | Deposit date: | 2013-02-25 | Release date: | 2013-03-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.26 Å) | Cite: | Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
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4JDV
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![BU of 4jdv by Molmil](/molmil-images/mine/4jdv) | Crystal structure of germ-line precursor of NIH45-46 Fab | Descriptor: | Fab heavy chain, Fab light chain, GLYCEROL, ... | Authors: | Diskin, R, Scharf, L, Bjorkman, P.J. | Deposit date: | 2013-02-25 | Release date: | 2013-03-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
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6TXZ
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![BU of 6txz by Molmil](/molmil-images/mine/6txz) | FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3 | Descriptor: | Fab H, Fab L, Hepatitis A virus cellular receptor 2 | Authors: | Musil, D, Sood, V. | Deposit date: | 2020-01-15 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology, 9, 2020
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6N6B
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![BU of 6n6b by Molmil](/molmil-images/mine/6n6b) | |
7DX4
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![BU of 7dx4 by Molmil](/molmil-images/mine/7dx4) | The structure of FC08 Fab-hA.CE2-RBD complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Heavy chain of FC08 Fab, ... | Authors: | Cao, L, Wang, X. | Deposit date: | 2021-01-18 | Release date: | 2021-04-21 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2. Natl Sci Rev, 8, 2021
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4FZE
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![BU of 4fze by Molmil](/molmil-images/mine/4fze) | |
1A14
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![BU of 1a14 by Molmil](/molmil-images/mine/1a14) | COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 5 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NC10 FV (HEAVY CHAIN), ... | Authors: | Malby, R.L, Mccoy, A.J, Kortt, A.A, Hudson, P.J, Colman, P.M. | Deposit date: | 1997-12-21 | Release date: | 1998-05-13 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Three-dimensional structures of single-chain Fv-neuraminidase complexes. J.Mol.Biol., 279, 1998
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6AMM
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![BU of 6amm by Molmil](/molmil-images/mine/6amm) | CAT192 Fab Insertion Mutant H0/L1 | Descriptor: | CAT192 Fab Heavy chain, CAT192 Fab Light chain | Authors: | Lord, D.M, Wei, R.R. | Deposit date: | 2017-08-10 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGF beta 1 antibody. MAbs, 10, 2018
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6AMJ
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![BU of 6amj by Molmil](/molmil-images/mine/6amj) | CAT192 Fab Wild Type | Descriptor: | CAT192 Fab heavy chain, CAT192 Fab light chain, DI(HYDROXYETHYL)ETHER, ... | Authors: | Lord, D.M, Wei, R.R. | Deposit date: | 2017-08-09 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGF beta 1 antibody. MAbs, 10, 2018
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6AO0
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![BU of 6ao0 by Molmil](/molmil-images/mine/6ao0) | CAT192 Fab Insertion Mutant H2/L2 | Descriptor: | CAT192 Fab Heavy chain, CAT192 Fab Light chain, SULFATE ION | Authors: | Lord, D.M, Wei, R.R. | Deposit date: | 2017-08-15 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGF beta 1 antibody. MAbs, 10, 2018
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3INU
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![BU of 3inu by Molmil](/molmil-images/mine/3inu) | Crystal structure of an unbound KZ52 neutralizing anti-Ebolavirus antibody. | Descriptor: | GLYCEROL, KZ52 antibody fragment heavy chain, KZ52 antibody fragment light chain, ... | Authors: | Lee, J.E, Fusco, M.L, Abelson, D.M, Hessell, A.J, Burton, D.R, Saphire, E.O. | Deposit date: | 2009-08-12 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Techniques and tactics used in determining the structure of the trimeric ebolavirus glycoprotein. Acta Crystallogr.,Sect.D, 65, 2009
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4FQL
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![BU of 4fql by Molmil](/molmil-images/mine/4fql) | Influenza B HA Antibody (Fab) CR8033 | Descriptor: | monoclonal antibody CR8033 heavy chain, monoclonal antibody CR8033 light chain | Authors: | Dreyfus, C, Laursen, N.S, Wilson, I.A. | Deposit date: | 2012-06-25 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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5T78
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![BU of 5t78 by Molmil](/molmil-images/mine/5t78) | Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, Fab Fragment - AR20.5 - Heavy chain, Fab fragment AR20.5 - Light Chain, ... | Authors: | Brooks, C.L, Movahedin, M. | Deposit date: | 2016-09-02 | Release date: | 2017-01-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen. Glycobiology, 27, 2017
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7CAI
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![BU of 7cai by Molmil](/molmil-images/mine/7cai) | SARS-CoV-2 S trimer with two RBDs in the open state and complexed with two H014 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H014 Fab, ... | Authors: | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Wang, Y, Rao, Z, Qin, C, Wang, X. | Deposit date: | 2020-06-08 | Release date: | 2020-09-23 | Last modified: | 2020-09-30 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Science, 369, 2020
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7CAH
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![BU of 7cah by Molmil](/molmil-images/mine/7cah) | The interface of H014 Fab binds to SARS-CoV-2 S | Descriptor: | Heavy chain of H014 Fab, Light chain of H014 Fab, Spike protein S1 | Authors: | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Rao, Z, wang, Y, Qin, C, Wang, X. | Deposit date: | 2020-06-08 | Release date: | 2020-08-12 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Science, 369, 2020
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7CAK
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![BU of 7cak by Molmil](/molmil-images/mine/7cak) | SARS-CoV-2 S trimer with three RBD in the open state and complexed with three H014 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H014 Fab, ... | Authors: | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Wang, Y, Rao, Z, Qin, C, Wang, X. | Deposit date: | 2020-06-08 | Release date: | 2020-09-23 | Last modified: | 2020-09-30 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Science, 369, 2020
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3EYV
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![BU of 3eyv by Molmil](/molmil-images/mine/3eyv) | Anti-Lewis Y Fab fragment with Lewis Y antigen in the presence of zinc ions | Descriptor: | GLYCEROL, ZINC ION, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, ... | Authors: | Farrugia, W, Scott, A.M, Ramsland, P.A. | Deposit date: | 2008-10-22 | Release date: | 2009-11-03 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A possible role for metallic ions in the carbohydrate cluster recognition displayed by a lewis y specific antibody. Plos One, 4, 2009
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1RVF
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![BU of 1rvf by Molmil](/molmil-images/mine/1rvf) | FAB COMPLEXED WITH INTACT HUMAN RHINOVIRUS | Descriptor: | FAB 17-IA, HUMAN RHINOVIRUS 14 COAT PROTEIN | Authors: | Smith, T.J. | Deposit date: | 1996-09-05 | Release date: | 1998-02-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Neutralizing antibody to human rhinovirus 14 penetrates the receptor-binding canyon. Nature, 383, 1996
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2EH8
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![BU of 2eh8 by Molmil](/molmil-images/mine/2eh8) | Crystal structure of the complex of humanized KR127 fab and PRES1 peptide epitope | Descriptor: | HUMANIZED KR127 FAB, HEAVY CHAIN, LIGHT CHAIN, ... | Authors: | Chi, S.-W, Kim, S.-J, Maeng, C.-Y, Hong, H.J, Ryu, S.-E. | Deposit date: | 2007-03-05 | Release date: | 2008-01-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Broadly neutralizing anti-hepatitis B virus antibody reveals a complementarity determining region H3 lid-opening mechanism Proc.Natl.Acad.Sci.Usa, 104, 2007
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3UYP
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![BU of 3uyp by Molmil](/molmil-images/mine/3uyp) | Crystal structure of the dengue virus serotype 4 envelope protein domain III in complex with the variable domains of Mab 4E11 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Envelope protein, GLYCEROL, ... | Authors: | Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A. | Deposit date: | 2011-12-06 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody. Structure, 20, 2012
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3UZE
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![BU of 3uze by Molmil](/molmil-images/mine/3uze) | Crystal structure of the dengue virus serotype 3 envelope protein domain III in complex with the variable domains of Mab 4E11 | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Envelope protein, ... | Authors: | Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A. | Deposit date: | 2011-12-07 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody. Structure, 20, 2012
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3UZV
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![BU of 3uzv by Molmil](/molmil-images/mine/3uzv) | Crystal structure of the dengue virus serotype 2 envelope protein domain III in complex with the variable domains of Mab 4E11 | Descriptor: | ETHANOL, anti-dengue Mab 4E11, envelope protein | Authors: | Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A. | Deposit date: | 2011-12-07 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody. Structure, 20, 2012
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