7DC7

Crystal structure of D12 Fab-ATP complex

Summary for 7DC7

• Entry DOI: 10.2210/pdb7dc7/pdb
• Descriptor: D12 Fab heavy chain, D12 Fab light chain, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: antibody, complex, fab, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 47570.46

Authors

Kawauchi, H.,Fukami, T.A.,Tatsumi, K.,Torizawa, T.,Mimoto, F. (deposition date: 2020-10-23, release date: 2021-01-13, Last modification date: 2023-11-29)

• Primary citation: Mimoto, F.,Tatsumi, K.,Shimizu, S.,Kadono, S.,Haraya, K.,Nagayasu, M.,Suzuki, Y.,Fujii, E.,Kamimura, M.,Hayasaka, A.,Kawauchi, H.,Ohara, K.,Matsushita, M.,Baba, T.,Susumu, H.,Sakashita, T.,Muraoka, T.,Aso, K.,Katada, H.,Tanaka, E.,Nakagawa, K.,Hasegawa, M.,Ayabe, M.,Yamamoto, T.,Tanba, S.,Ishiguro, T.,Kamikawa, T.,Nambu, T.,Kibayashi, T.,Azuma, Y.,Tomii, Y.,Kato, A.,Ozeki, K.,Murao, N.,Endo, M.,Kikuta, J.,Kamata-Sakurai, M.,Ishii, M.,Hattori, K.,Igawa, T.; Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment.; Cell Rep, 33:108542-108542, 2020; PubMed: 33357423; DOI: 10.1016/j.celrep.2020.108542

Experimental method

X-RAY DIFFRACTION (1.77 Å)