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7DX4

The structure of FC08 Fab-hA.CE2-RBD complex

Summary for 7DX4
Entry DOI10.2210/pdb7dx4/pdb
EMDB information30895
DescriptorAngiotensin-converting enzyme 2, Spike protein S1, Heavy chain of FC08 Fab, ... (5 entities in total)
Functional Keywordssars-cov-2, spike, neutralizing antibody, hace2, rbd, viral protein
Biological sourceHomo sapiens (Human)
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Total number of polymer chains4
Total formula weight116855.48
Authors
Cao, L.,Wang, X. (deposition date: 2021-01-18, release date: 2021-04-21, Last modification date: 2022-02-23)
Primary citationZhang, L.,Cao, L.,Gao, X.S.,Zheng, B.Y.,Deng, Y.Q.,Li, J.X.,Feng, R.,Bian, Q.,Guo, X.L.,Wang, N.,Qiu, H.Y.,Wang, L.,Cui, Z.,Ye, Q.,Chen, G.,Lu, K.K.,Chen, Y.,Chen, Y.T.,Pan, H.X.,Yu, J.,Yao, W.,Zhu, B.L.,Chen, J.,Liu, Y.,Qin, C.F.,Wang, X.,Zhu, F.C.
A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2.
Natl Sci Rev, 8:nwab053-nwab053, 2021
Cited by
PubMed: 34676098
DOI: 10.1093/nsr/nwab053
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.6 Å)
Structure validation

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