2EH8

Crystal structure of the complex of humanized KR127 fab and PRES1 peptide epitope

Summary for 2EH8

Related2EH7
DescriptorHUMANIZED KR127 FAB, LIGHT CHAIN, HUMANIZED KR127 FAB, HEAVY CHAIN, PreS1/PreS2/surface protein, ... (4 entities in total)
Functional Keywordshepatitis b virus, humanized antibody, monoclonal antibody, neutralization, pres1, immune system
Biological sourceMus musculus (house mouse)
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Total number of polymer chains3
Total molecular weight48168.6
Authors
Chi, S.-W.,Kim, S.-J.,Maeng, C.-Y.,Hong, H.J.,Ryu, S.-E. (deposition date: 2007-03-05, release date: 2008-01-15, Last modification date: 2017-10-11)
Primary citation
Chi, S.-W.,Maeng, C.-Y.,Kim, S.J.,Oh, M.S.,Ryu, C.J.,Kim, S.-J.,Han, K.-H.,Hong, H.J.,Ryu, S.-E.
Broadly neutralizing anti-hepatitis B virus antibody reveals a complementarity determining region H3 lid-opening mechanism
Proc.Natl.Acad.Sci.Usa, 104:9230-9235, 2007
PubMed: 17517649 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0701279104
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.255130.9%4.2%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution