6KIV
 
 | | Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom) | | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Huang, J, Xue, H, Yao, T. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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8TB9
 | | PRC2-J119-450 monomer bound to H1-nucleosome | | Descriptor: | DNA (226-MER), Histone H1.0, Histone H2A type 1, ... | | Authors: | Sauer, P.V, Cookis, T, Pavlenko, E, Nogales, E, Poepsel, S. | | Deposit date: | 2023-06-28 | | Release date: | 2024-09-25 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Activation of automethylated PRC2 by dimerization on chromatin.
Mol.Cell, 2024
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8CBQ
 | | structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome | | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | | Authors: | Koutna, E, Kouba, T, Novacek, J, Veverka, V. | | Deposit date: | 2023-01-25 | | Release date: | 2023-09-06 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
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8BVW
 | | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | | Deposit date: | 2022-12-20 | | Release date: | 2023-05-03 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
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6FQ6
 | | Class 2 : distorted nucleosome | | Descriptor: | DNA (147-MER), Histone H2A, Histone H2B, ... | | Authors: | Bilokapic, S, Halic, M. | | Deposit date: | 2018-02-13 | | Release date: | 2018-04-18 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural rearrangements of the histone octamer translocate DNA.
Nat Commun, 9, 2018
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6RYU
 | | Nucleosome-CHD4 complex structure (two CHD4 copies) | | Descriptor: | Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | | Authors: | Farnung, L, Ochmann, M, Cramer, P. | | Deposit date: | 2019-06-12 | | Release date: | 2020-07-15 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
Elife, 9, 2020
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6R1T
 | | Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome | | Descriptor: | DNA (147-MER), HISTONE H2A, Histone H2A, ... | | Authors: | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | | Deposit date: | 2019-03-15 | | Release date: | 2019-04-24 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.02 Å) | | Cite: | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
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6PX3
 | | Set2 bound to nucleosome | | Descriptor: | DNA (145-MER), Histone H2B 1.1, Histone H3, ... | | Authors: | Halic, M, Bilokapic, S. | | Deposit date: | 2019-07-24 | | Release date: | 2019-08-28 | | Last modified: | 2019-09-04 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Nucleosome and ubiquitin position Set2 to methylate H3K36.
Nat Commun, 10, 2019
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6KIX
 | | Cryo-EM structure of human MLL1-NCP complex, binding mode1 | | Descriptor: | DNA (145-MER), GLUTAMINE, Histone H2A, ... | | Authors: | Huang, J, Xue, H, Yao, T. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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8BYQ
 | | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | | Deposit date: | 2022-12-14 | | Release date: | 2023-05-03 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
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9GD2
 | | Structure of Chd1 bound to a dinucleosome with a dyad-to-dyad distance of 103 bp. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | | Authors: | Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. | | Deposit date: | 2024-08-04 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
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6PWX
 | | Cryo-EM structure of RbBP5 bound to the nucleosome | | Descriptor: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | | Authors: | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | | Deposit date: | 2019-07-23 | | Release date: | 2019-12-18 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
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7UD5
 | | Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome | | Descriptor: | 601 DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Niklas, H.A, Rahman, S, Worden, E.J, Wolberger, C. | | Deposit date: | 2022-03-18 | | Release date: | 2022-09-21 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (4.25 Å) | | Cite: | Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5Z3L
 | | Structure of Snf2-nucleosome complex in apo state | | Descriptor: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | | Deposit date: | 2018-01-08 | | Release date: | 2019-04-03 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.31 Å) | | Cite: | Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
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6R1U
 | | Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2 | | Descriptor: | DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A, ... | | Authors: | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | | Deposit date: | 2019-03-15 | | Release date: | 2019-04-24 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.36 Å) | | Cite: | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
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7AT8
 | | Histone H3 recognition by nucleosome-bound PRC2 subunit EZH2. | | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3.2, ... | | Authors: | Finogenova, K, Benda, C, Schaefer, I.B, Poepsel, S, Strauss, M, Mueller, J. | | Deposit date: | 2020-10-29 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3.
Elife, 9, 2020
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6I84
 | | Structure of transcribing RNA polymerase II-nucleosome complex | | Descriptor: | DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Farnung, L, Vos, S.M, Cramer, P. | | Deposit date: | 2018-11-19 | | Release date: | 2019-01-02 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structure of transcribing RNA polymerase II-nucleosome complex.
Nat Commun, 9, 2018
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6PWW
 | | Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome | | Descriptor: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | | Authors: | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | | Deposit date: | 2019-07-23 | | Release date: | 2019-12-18 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
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6Z6P
 | | HDAC-PC-Nuc | | Descriptor: | DNA (145-MER), HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, ... | | Authors: | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | | Deposit date: | 2020-05-28 | | Release date: | 2021-02-17 | | Method: | ELECTRON MICROSCOPY (4.43 Å) | | Cite: | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
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5HQ2
 | | Structural model of Set8 histone H4 Lys20 methyltransferase bound to nucleosome core particle | | Descriptor: | DNA (149-MER), Guanine nucleotide exchange factor SRM1, Histone H2A, ... | | Authors: | Tavarekere, G, McGinty, R.K, Tan, S. | | Deposit date: | 2016-01-21 | | Release date: | 2016-03-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate.
J.Mol.Biol., 428, 2016
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6KIZ
 | | Cryo-EM structure of human MLL1-NCP complex, binding mode2 | | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Huang, J, Xue, H, Yao, T. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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6FTX
 | | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin-remodeling ATPase, ... | | Authors: | Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. | | Deposit date: | 2018-02-25 | | Release date: | 2018-08-08 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome.
Elife, 7, 2018
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6W5M
 | | Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02) | | Descriptor: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | | Authors: | Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. | | Deposit date: | 2020-03-13 | | Release date: | 2021-03-31 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Nat Commun, 12, 2021
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6R25
 | | Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3 | | Descriptor: | DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, H2B, ... | | Authors: | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | | Deposit date: | 2019-03-15 | | Release date: | 2019-04-24 | | Method: | ELECTRON MICROSCOPY (4.61 Å) | | Cite: | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
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5X0Y
 | | Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome | | Descriptor: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Li, M, Liu, X, Xia, X, Chen, Z, Li, X. | | Deposit date: | 2017-01-23 | | Release date: | 2017-04-19 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.69 Å) | | Cite: | Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Nature, 544, 2017
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