8CBQ

structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome

Summary for 8CBQ

Entry DOI	10.2210/pdb8cbq/pdb
EMDB information	10069 16549
Descriptor	Histone H4, Histone H2A, Histone H2B 1.1, ... (7 entities in total)
Functional Keywords	nucleosome, transcription activator, methylation, complex, dna binding protein
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	11
Total formula weight	270290.78
Authors	Koutna, E.,Kouba, T.,Novacek, J.,Veverka, V. (deposition date: 2023-01-25, release date: 2023-09-06, Last modification date: 2023-11-15)
Primary citation	Koutna, E.,Lux, V.,Kouba, T.,Skerlova, J.,Novacek, J.,Srb, P.,Hexnerova, R.,Svachova, H.,Kukacka, Z.,Novak, P.,Fabry, M.,Poepsel, S.,Veverka, V. Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51:10011-10025, 2023 Cited by PubMed: 37615563 DOI: 10.1093/nar/gkad674 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation