6R1I
| Structure of porcine Aichi virus polymerase | Descriptor: | Genome polyprotein | Authors: | Dubankova, A, Boura, E. | Deposit date: | 2019-03-14 | Release date: | 2019-10-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.634 Å) | Cite: | Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation. J.Struct.Biol., 208, 2019
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5XE0
| Crystal structure of EV-D68-3Dpol in complex with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein | Authors: | Xie, W, Wang, C, Wang, Z, Li, Q, Wang, C. | Deposit date: | 2017-03-30 | Release date: | 2017-06-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol J. Virol., 91, 2017
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5JXS
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5TSN
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1WNE
| Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA | Descriptor: | 5'-R(*CP*AP*UP*GP*GP*GP*CP*C)-3', 5'-R(*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2004-07-31 | Release date: | 2004-08-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA J.Biol.Chem., 279, 2004
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6S2L
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3DDK
| Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase | Descriptor: | RNA polymerase B3 3Dpol, SODIUM ION, SULFATE ION | Authors: | Campagnola, G, Weygandt, M.H, Scoggin, K.E, Peersen, O.B. | Deposit date: | 2008-06-05 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structure of Coxsackievirus B3 3Dpol Highlights Functional Importance of Residue 5 in Picornaviral Polymerases J.Virol., 82, 2008
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4B02
| The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M. | Deposit date: | 2012-06-27 | Release date: | 2012-08-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase. Virology, 432, 2012
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6QWT
| Sicinivirus 3Dpol RNA dependent RNA polymerase | Descriptor: | Genome polyprotein | Authors: | Dubankova, A, Boura, E. | Deposit date: | 2019-03-06 | Release date: | 2019-10-09 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation. J.Struct.Biol., 208, 2019
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4IKA
| Crystal structure of EV71 3Dpol-VPg | Descriptor: | 3Dpol, NICKEL (II) ION, VPg | Authors: | Chen, C, Wang, Y.X, Lou, Z.Y. | Deposit date: | 2012-12-25 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: implication for a trans mechanism of VPg uridylylation J.Virol., 87, 2013
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7W9S
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5F8J
| Enterovirus 71 Polymerase Elongation Complex (C1S4 Form) | Descriptor: | GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... | Authors: | Shu, B, Gong, P. | Deposit date: | 2015-12-09 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.675 Å) | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
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3CDU
| Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. | Deposit date: | 2008-02-27 | Release date: | 2008-07-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
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3CDW
| Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. | Deposit date: | 2008-02-27 | Release date: | 2008-07-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
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8C2P
| FMDV 3D polymerase in complex with 3B3 | Descriptor: | Protein 3B-3, RNA-directed RNA polymerase 3D-POL | Authors: | Ferrer-Orta, C, Veraguer, N. | Deposit date: | 2022-12-22 | Release date: | 2023-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes. Plos Pathog., 19, 2023
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8C1N
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3H5Y
| Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2 | Descriptor: | 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S. | Deposit date: | 2009-04-22 | Release date: | 2009-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site. J.Mol.Biol., 390, 2009
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8IIB
| Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546) | Descriptor: | CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Fang, X, Lu, G, Hou, C, Gong, P. | Deposit date: | 2023-02-24 | Release date: | 2023-06-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding. Virol Sin, 38, 2023
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8IIC
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5N8X
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5N95
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6GVV
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6GVY
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3H5X
| Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase | Descriptor: | 2'-amino-2'-deoxycytidine 5'-(tetrahydrogen triphosphate), 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ... | Authors: | Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S. | Deposit date: | 2009-04-22 | Release date: | 2009-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site. J.Mol.Biol., 390, 2009
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1RA7
| Poliovirus Polymerase with GTP | Descriptor: | ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein | Authors: | Thompson, A.A, Peersen, O.B. | Deposit date: | 2003-10-31 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase. Embo J., 23, 2004
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