3DRT
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![BU of 3drt by Molmil](/molmil-images/mine/3drt) | Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 scrambledFP-MPER scrHyb3K construct GIGAFGLLGFLAAGSKK-Ahx-K656NEQELLELDKWASLWN671 | Descriptor: | 2F5 Fab' heavy chain, 2F5 Fab' light chain, GLYCEROL, ... | Authors: | Julien, J.-P, Bryson, S, de la Torre, B.G, Andreu, D, Nieva, J.L, Pai, E.F. | Deposit date: | 2008-07-11 | Release date: | 2009-06-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5. J.Phys.Chem.B, 113, 2009
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7K7H
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![BU of 7k7h by Molmil](/molmil-images/mine/7k7h) | Density-fitted Model Structure of Antibody Variable Domains of TyTx1 in Complex with PltB pentamer of Typhoid Toxin | Descriptor: | Fab Heavy Chain Variable Domain, Fab Light Chain Variable Domain, Pertussis like toxin subunit B, ... | Authors: | Nguyen, T, Feathers, J.R, Fromme, J.C, Song, J. | Deposit date: | 2020-09-22 | Release date: | 2021-09-01 | Last modified: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits. Cell Rep, 36, 2021
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7K7I
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![BU of 7k7i by Molmil](/molmil-images/mine/7k7i) | Density-fitted Model Structure of Antibody Variable Domains of TyTx4 in Complex with PltB pentamer of Typhoid Toxin | Descriptor: | Fab Heavy Chain Variable Domain, Fab Light Chain Variable Domain, Putative pertussis-like toxin subunit | Authors: | Nguyen, T, Feathers, J.R, Fromme, J.C, Song, J. | Deposit date: | 2020-09-22 | Release date: | 2021-09-01 | Last modified: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits. Cell Rep, 36, 2021
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1FVC
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![BU of 1fvc by Molmil](/molmil-images/mine/1fvc) | X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING | Descriptor: | IGG1-KAPPA 4D5 FV (HEAVY CHAIN), IGG1-KAPPA 4D5 FV (LIGHT CHAIN) | Authors: | Eigenbrot, C, Randal, M, Kossiakoff, A.A, Presta, L. | Deposit date: | 1992-10-20 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling. J.Mol.Biol., 229, 1993
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1I3G
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![BU of 1i3g by Molmil](/molmil-images/mine/1i3g) | CRYSTAL STRUCTURE OF AN AMPICILLIN SINGLE CHAIN FV, FORM 1, FREE | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ANTIBODY FV FRAGMENT | Authors: | Jung, S, Spinelli, S, Schimmele, B, Honegger, A, Pugliese, L, Cambillau, C, Pluckthun, A. | Deposit date: | 2001-02-15 | Release date: | 2001-10-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries. J.Mol.Biol., 309, 2001
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6P3B
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![BU of 6p3b by Molmil](/molmil-images/mine/6p3b) | |
7WPV
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![BU of 7wpv by Molmil](/molmil-images/mine/7wpv) | Fab14 - a SARS-CoV2 RBD neutralising antibody | Descriptor: | Fab14 heavy chain, Fab14 light chain | Authors: | Lin, J.Q, El Sahili, A, Lescar, J. | Deposit date: | 2022-01-24 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth. Nat Commun, 13, 2022
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7MMN
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![BU of 7mmn by Molmil](/molmil-images/mine/7mmn) | |
1R24
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![BU of 1r24 by Molmil](/molmil-images/mine/1r24) | FAB FROM MURINE IGG3 KAPPA | Descriptor: | PROTEIN (IGG3-KAPPA ANTIBODY (HEAVY CHAIN)), PROTEIN (IGG3-KAPPA ANTIBODY (LIGHT CHAIN)) | Authors: | Evans, S.V. | Deposit date: | 1998-11-05 | Release date: | 1999-11-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains. J.Biol.Chem., 274, 1999
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3EGS
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![BU of 3egs by Molmil](/molmil-images/mine/3egs) | Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 scrambledFP-MPER scrHyb3K construct GIGAFGLLGFLAAGSKK-Ahx-K656NEQELLELDKWASLWN671 soaked in ammonium sulfate | Descriptor: | 2F5 Fab' heavy chain, 2F5 Fab' light chain, gp41 scrFP-MPER construct | Authors: | Julien, J.-P, Bryson, S, de la Torre, B.G, Andreu, D, Nieva, J.L, Pai, E.F. | Deposit date: | 2008-09-11 | Release date: | 2009-08-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5. J.Phys.Chem.B, 113, 2009
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1BBD
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![BU of 1bbd by Molmil](/molmil-images/mine/1bbd) | |
1F4Y
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![BU of 1f4y by Molmil](/molmil-images/mine/1f4y) | CRYSTAL STRUCTURE OF AN ANTI-CARBOHYDRATE ANTIBODY DIRECTED AGAINST VIBRIO CHOLERAE O1 IN COMPLEX WITH ANTIGEN | Descriptor: | 4,6-dideoxy-4-{[(2R)-2,4-dihydroxybutanoyl]amino}-2-O-methyl-alpha-D-mannopyranose-(1-2)-methyl 4,6-dideoxy-4-{[(2R)-2,4-dihydroxybutanoyl]amino}-alpha-D-mannopyranoside, ANTIBODY S-20-4, FAB FRAGMENT, ... | Authors: | Alzari, P.M, Souchon, H. | Deposit date: | 2000-06-10 | Release date: | 2000-08-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of an anti-carbohydrate antibody directed against Vibrio cholerae O1 in complex with antigen: molecular basis for serotype specificity. Proc.Natl.Acad.Sci.USA, 97, 2000
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3QEG
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![BU of 3qeg by Molmil](/molmil-images/mine/3qeg) | Crystal structure of human N12-i2 Fab, an ADCC and neutralizing anti-HIV-1 Env antibody | Descriptor: | Fab fragment of human anti-HIV antibody N12-i2, heavy chain, light chain | Authors: | Guan, Y, DeVico, A.L, Lewis, G.K, Pazgier, M. | Deposit date: | 2011-01-20 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of human N12-i2 Fab, an ADCC and neutralizing anti-HIV-1 Env antibody To be Published
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1FVD
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![BU of 1fvd by Molmil](/molmil-images/mine/1fvd) | X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING | Descriptor: | IGG1-KAPPA 4D5 FAB (HEAVY CHAIN), IGG1-KAPPA 4D5 FAB (LIGHT CHAIN) | Authors: | Eigenbrot, C, Presta, L, Randal, M, Kossiakoff, A.A. | Deposit date: | 1992-10-20 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling. J.Mol.Biol., 229, 1993
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3RVT
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![BU of 3rvt by Molmil](/molmil-images/mine/3rvt) | Structure of 4C1 Fab in P212121 space group | Descriptor: | Fab fragment of 4C1 antibody - heavy chain, Fab fragment of 4C1 antibody - light chain | Authors: | Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W. | Deposit date: | 2011-05-06 | Release date: | 2012-01-11 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Molecular determinants for antibody binding on group 1 house dust mite allergens. J.Biol.Chem., 287, 2012
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6ITQ
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![BU of 6itq by Molmil](/molmil-images/mine/6itq) | Crystal structure of cortisol complexed with its nanobody at pH 10.5 | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, SULFATE ION, anti-cortisol camelid antibody | Authors: | Ding, Y, Ding, L.L, Wang, Z.Y, Zhong, P.Y. | Deposit date: | 2018-11-24 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.526 Å) | Cite: | Structural insights into the mechanism of single domain VHH antibody binding to cortisol. Febs Lett., 593, 2019
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6X78
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![BU of 6x78 by Molmil](/molmil-images/mine/6x78) | |
6X7W
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![BU of 6x7w by Molmil](/molmil-images/mine/6x7w) | |
5LBV
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![BU of 5lbv by Molmil](/molmil-images/mine/5lbv) | Structural basis of zika and dengue virus potent antibody cross-neutralization | Descriptor: | SODIUM ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, envelope protein E | Authors: | Barba-Spaeth, G. | Deposit date: | 2016-06-17 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of potent Zika-dengue virus antibody cross-neutralization. Nature, 536, 2016
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4ZSO
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![BU of 4zso by Molmil](/molmil-images/mine/4zso) | Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | Authors: | Xu, X, Li, Y, Mariuzza, R.A. | Deposit date: | 2015-05-13 | Release date: | 2016-05-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody to be published
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6ZDH
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![BU of 6zdh by Molmil](/molmil-images/mine/6zdh) | SARS-CoV-2 Spike glycoprotein in complex with a neutralizing antibody EY6A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2020-06-14 | Release date: | 2020-07-01 | Last modified: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
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7PC2
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![BU of 7pc2 by Molmil](/molmil-images/mine/7pc2) | HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC IgG Fab heavy chain, ... | Authors: | Fernandez, I, Bontems, F, Pehau-Arnaudet, G, Rey, F. | Deposit date: | 2021-08-03 | Release date: | 2022-02-23 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller. J.Exp.Med., 219, 2022
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6ITP
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![BU of 6itp by Molmil](/molmil-images/mine/6itp) | Crystal structure of cortisol complexed with its nanobody at pH 3.5 | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, anti-cortisol camelid antibody | Authors: | Ding, Y, Ding, L.L, Wang, Z.Y, Zhong, P.Y. | Deposit date: | 2018-11-24 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.572 Å) | Cite: | Structural insights into the mechanism of single domain VHH antibody binding to cortisol. Febs Lett., 593, 2019
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3QXW
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![BU of 3qxw by Molmil](/molmil-images/mine/3qxw) | Free structure of an anti-methotrexate CDR1-4 Graft VHH Antibody | Descriptor: | Anti-Methotrexate CDR1-4 Graft VHH, SODIUM ION, SULFATE ION | Authors: | Fanning, S.W, Horn, J.R. | Deposit date: | 2011-03-02 | Release date: | 2011-07-27 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. Protein Sci., 20, 2011
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3RA7
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![BU of 3ra7 by Molmil](/molmil-images/mine/3ra7) | |