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6ITP

Crystal structure of cortisol complexed with its nanobody at pH 3.5

Summary for 6ITP
Entry DOI10.2210/pdb6itp/pdb
Descriptoranti-cortisol camelid antibody, (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione (3 entities in total)
Functional Keywordscortisol, complex, nanobody, camelid antibody, immune system
Biological sourceCamelus bactrianus
Total number of polymer chains2
Total formula weight28285.11
Authors
Ding, Y.,Ding, L.L.,Wang, Z.Y.,Zhong, P.Y. (deposition date: 2018-11-24, release date: 2019-07-24, Last modification date: 2023-11-22)
Primary citationDing, L.,Wang, Z.,Zhong, P.,Jiang, H.,Zhao, Z.,Zhang, Y.,Ren, Z.,Ding, Y.
Structural insights into the mechanism of single domain VHH antibody binding to cortisol.
Febs Lett., 593:1248-1256, 2019
Cited by
PubMed: 31049949
DOI: 10.1002/1873-3468.13398
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.572 Å)
Structure validation

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