7WPV

Fab14 - a SARS-CoV2 RBD neutralising antibody

Summary for 7WPV

Entry DOI	10.2210/pdb7wpv/pdb
Descriptor	Fab14 light chain, Fab14 heavy chain (3 entities in total)
Functional Keywords	sars-cov2 rbd neutralising antibody, protein binding, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	48102.32
Authors	Lin, J.Q.,El Sahili, A.,Lescar, J. (deposition date: 2022-01-24, release date: 2022-03-30, Last modification date: 2023-11-29)
Primary citation	Ku, Z.,Xie, X.,Lin, J.,Gao, P.,Wu, B.,El Sahili, A.,Su, H.,Liu, Y.,Ye, X.,Tan, E.Y.,Li, X.,Fan, X.,Goh, B.C.,Xiong, W.,Boyd, H.,Muruato, A.E.,Deng, H.,Xia, H.,Zou, J.,Kalveram, B.K.,Menachery, V.D.,Zhang, N.,Lescar, J.,Shi, P.Y.,An, Z. Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth. Nat Commun, 13:5552-5552, 2022 Cited by PubMed: 36138032 DOI: 10.1038/s41467-022-33284-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.46 Å)

Structure validation