3EGS
Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 scrambledFP-MPER scrHyb3K construct GIGAFGLLGFLAAGSKK-Ahx-K656NEQELLELDKWASLWN671 soaked in ammonium sulfate
Summary for 3EGS
| Entry DOI | 10.2210/pdb3egs/pdb |
| Related | 3D0L 3DRQ 3DRT |
| Descriptor | 2F5 Fab' light chain, 2F5 Fab' heavy chain, gp41 scrFP-MPER construct (3 entities in total) |
| Functional Keywords | 2f5, gp41, hiv, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 3 |
| Total formula weight | 52171.69 |
| Authors | Julien, J.-P.,Bryson, S.,de la Torre, B.G.,Andreu, D.,Nieva, J.L.,Pai, E.F. (deposition date: 2008-09-11, release date: 2009-08-25, Last modification date: 2023-11-15) |
| Primary citation | de la Arada, I.,Julien, J.P.,de la Torre, B.G.,Huarte, N.,Andreu, D.,Pai, E.F.,Arrondo, J.L.,Nieva, J.L. Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5. J.Phys.Chem.B, 113:13626-13637, 2009 Cited by PubMed: 19754136DOI: 10.1021/jp905965h PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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