3D0L

Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 FP-MPER Hyb3K construct 514GIGALFLGFLGAAGS528KK-Ahx-655KNEQELLELDKWASLWN671

Summary for 3D0L

Entry DOI	10.2210/pdb3d0l/pdb
Related	1TJH 2P8L 2P8M 2P8P 2PR4 3d0v
Descriptor	2F5 heavy chain, 2F5 light chain, Hyb3k peptide construct, ... (6 entities in total)
Functional Keywords	hiv, antibody, neutralization, epitope, 2f5, gp41, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	52773.23
Authors	Bryson, S.,Julien, J.P.,Pai, E.F. (deposition date: 2008-05-01, release date: 2008-10-07, Last modification date: 2023-11-15)
Primary citation	Julien, J.P.,Bryson, S.,Nieva, J.L.,Pai, E.F. Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384:377-392, 2008 Cited by PubMed: 18824005 DOI: 10.1016/j.jmb.2008.09.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation