3QEG

Crystal structure of human N12-i2 Fab, an ADCC and neutralizing anti-HIV-1 Env antibody

Summary for 3QEG

• Entry DOI: 10.2210/pdb3qeg/pdb
• Related: 3QEH
• Descriptor: Fab fragment of human anti-HIV antibody N12-i2, heavy chain, Fab fragment of human anti-HIV antibody N12-i2, light chain (3 entities in total)
• Functional Keywords: adcc and neutralizing anti-hiv-1 env antibody n12-i2, cd4i antibody, fab fragment, binds to viral glycoprotein gp120, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 49088.56

Authors

Guan, Y.,DeVico, A.L.,Lewis, G.K.,Pazgier, M. (deposition date: 2011-01-20, release date: 2012-01-25, Last modification date: 2024-11-27)

• Primary citation: Guan, Y.,DeVico, A.L.,Lewis, G.K.,Pazgier, M.; Crystal structure of human N12-i2 Fab, an ADCC and neutralizing anti-HIV-1 Env antibody; To be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)