3QXW

Free structure of an anti-methotrexate CDR1-4 Graft VHH Antibody

Summary for 3QXW

Entry DOI	10.2210/pdb3qxw/pdb
Related	1I3U 2x6m 3QXT 3QXU 3QXV
Descriptor	Anti-Methotrexate CDR1-4 Graft VHH, SODIUM ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	camelid single domain antibody, heavy chain only, vhh, antibody, anti-hapten antibody, cdr, hapten binding, small molecule sensing, ligand binding, low molecular weight compound, methotrexate, immune system
Biological source	Lama Glama (Llama)
Total number of polymer chains	5
Total formula weight	69025.94
Authors	Fanning, S.W.,Horn, J.R. (deposition date: 2011-03-02, release date: 2011-07-27, Last modification date: 2019-12-25)
Primary citation	Fanning, S.W.,Horn, J.R. An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. Protein Sci., 20:1196-1207, 2011 Cited by PubMed: 21557375 DOI: 10.1002/pro.648 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation