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7U2B
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BU of 7u2b by Molmil
Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA(GCU-TL)
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, RNA (53-MER), Serine--tRNA ligase, ...
Authors:Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G.
Deposit date:2022-02-23
Release date:2022-09-14
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA.
Nat Commun, 13, 2022
7U2A
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BU of 7u2a by Molmil
Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA (GCU)
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, RNA (38-MER), Serine--tRNA ligase, ...
Authors:Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G.
Deposit date:2022-02-23
Release date:2022-09-14
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA.
Nat Commun, 13, 2022
6LVR
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BU of 6lvr by Molmil
Crystal structure of the PPR domain of Arabidopsis thaliana protein-only RNase P 1 (PRORP1) in complex with tRNA
Descriptor: Proteinaceous RNase P 1, chloroplastic/mitochondrial, yeast phenylalanine tRNA
Authors:Teramoto, T, Hall, T.M.T.
Deposit date:2020-02-04
Release date:2020-08-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Pentatricopeptide repeats of protein-only RNase P use a distinct mode to recognize conserved bases and structural elements of pre-tRNA.
Nucleic Acids Res., 48, 2020
7S3B
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BU of 7s3b by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide
Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7OQB
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BU of 7oqb by Molmil
The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)
Descriptor: ACT1 pre-mRNA (delta-BS-A), Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing ATP-dependent RNA helicase PRP5, ...
Authors:Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R.
Deposit date:2021-06-03
Release date:2021-08-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
5YDT
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BU of 5ydt by Molmil
Remodeled Utp30 in 90S pre-ribosome (Mtr4-depleted, Enp1-TAP)
Descriptor: 5' ETS RNA, Ribosome biogenesis protein UTP30, Saccharomyces cerevisiae strain ALI 308 18S ribosomal RNA gene, ...
Authors:Ye, K, Zhu, X, Hu, J.
Deposit date:2017-09-14
Release date:2017-11-01
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and RNA recognition of ribosome assembly factor Utp30.
RNA, 23, 2017
6FQ1
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BU of 6fq1 by Molmil
Crystal structure of the RRM12 domain of IMP3
Descriptor: 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-02-12
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
8PV8
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BU of 8pv8 by Molmil
Chaetomium thermophilum pre-60S State 4 - post-5S rotation with Rix1 complex without Foot - composite structure
Descriptor: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
Deposit date:2023-07-17
Release date:2024-01-10
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
8V1H
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BU of 8v1h by Molmil
Crystal structure of human pre-mascRNA
Descriptor: SODIUM ION, pre-mascRNA
Authors:Skeparnias, I, Zhang, J.
Deposit date:2023-11-20
Release date:2024-07-10
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structural basis of MALAT1 RNA maturation and mascRNA biogenesis.
Nat.Struct.Mol.Biol., 31, 2024
7UO1
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BU of 7uo1 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: CALCIUM ION, E.coli RNase P RNA, Precursor tRNA substrate U(-1) and A(-2), ...
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
1VY4
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BU of 1vy4 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing acylated tRNA-substrates in the A and P sites.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Steitz, T.A, Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
8OPS
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BU of 8ops by Molmil
Human terminal uridylyltransferase 7 (TUT7/ZCCHC6) bound with pre-let7g miRNA and Lin28A - complex 1
Descriptor: Protein lin-28 homolog A, RNA (71-MER) Let7g, Terminal uridylyltransferase 7, ...
Authors:Yi, G, Ye, M, Gilbert, R.J.
Deposit date:2023-04-08
Release date:2024-07-24
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs.
Nat.Struct.Mol.Biol., 31, 2024
8OPT
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BU of 8opt by Molmil
Human terminal uridylyltransferase 7 (TUT7/ZCCHC6) bound with pre-let7g miRNA and Lin28A - complex 2
Descriptor: Protein lin-28 homolog A, RNA (53-MER), Terminal uridylyltransferase 7, ...
Authors:Yi, G, Ye, M, Gilbert, R.J.
Deposit date:2023-04-08
Release date:2024-07-24
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs.
Nat.Struct.Mol.Biol., 31, 2024
7UO0
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BU of 7uo0 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: CALCIUM ION, Precursor tRNA substrate G(-1) G(-2), RNase P RNA, ...
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
1MJI
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BU of 1mji by Molmil
DETAILED ANALYSIS OF RNA-PROTEIN INTERACTIONS WITHIN THE BACTERIAL RIBOSOMAL PROTEIN L5/5S RRNA COMPLEX
Descriptor: 50S ribosomal protein L5, 5S rRNA fragment, MAGNESIUM ION, ...
Authors:Perederina, A, Nevskaya, N, Nikonov, O, Nikulin, A, Dumas, P, Yao, M, Tanaka, I, Garber, M, Gongadze, G, Nikonov, S.
Deposit date:2002-08-28
Release date:2003-01-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Detailed analysis of RNA-protein interactions within the bacterial ribosomal protein L5/5S rRNA complex
RNA, 8, 2002
7OQC
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BU of 7oqc by Molmil
The U1 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A), Pre-mRNA-processing factor 39, ...
Authors:Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R.
Deposit date:2021-06-03
Release date:2021-08-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
1VY7
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BU of 1vy7 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Cytidine-Puromycin in the A site and acylated tRNA in the P site.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Steitz, T.A, Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VY6
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BU of 1vy6 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Puromycin in the A site and acylated tRNA in the P site.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Steitz, T.A, Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
7UO2
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BU of 7uo2 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: MAGNESIUM ION, RNase P RNA, Ribonuclease P protein component
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
7UO5
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BU of 7uo5 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: CALCIUM ION, RNase P RNA, Ribonuclease P protein component
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
3OTO
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BU of 3oto by Molmil
Crystal Structure of the 30S ribosomal subunit from a KsgA mutant of Thermus thermophilus (HB8)
Descriptor: 16S rRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Demirci, H, Murphy IV, F, Belardinelli, R, Kelley, A.C, Ramakrishnan, V, Gregory, S.T, Dahlberg, A.E, Jogl, G.
Deposit date:2010-09-13
Release date:2010-09-29
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.69 Å)
Cite:Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
Rna, 16, 2010
2B63
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BU of 2b63 by Molmil
Complete RNA Polymerase II-RNA inhibitor complex
Descriptor: 31-MER, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ...
Authors:Kettenberger, H, Eisenfuehr, A, Brueckner, F, Theis, M, Famulok, M, Cramer, P.
Deposit date:2005-09-30
Release date:2005-12-06
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs
Nat.Struct.Mol.Biol., 13, 2006
6SPC
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BU of 6spc by Molmil
Pseudomonas aeruginosa 30s ribosome from an aminoglycoside resistant clinical isolate
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Halfon, Y, Jimenez-Fernande, A, La Ros, R, Espinos, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S, Yonath, A.
Deposit date:2019-09-01
Release date:2019-10-16
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Proc.Natl.Acad.Sci.USA, 116, 2019
7ZGR
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BU of 7zgr by Molmil
Polymerase module of yeast CPF in complex with Mpe1, the yPIM of Cft2 and the pre-cleaved CYC1 RNA
Descriptor: Cleavage factor two protein 2, MPE1 isoform 1, Polyadenylation factor subunit 2, ...
Authors:Rodriguez-Molina, J.B, Passmore, L.A.
Deposit date:2022-04-04
Release date:2022-05-25
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
6LR6
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BU of 6lr6 by Molmil
The crystal structure of human cytoplasmic LRS
Descriptor: 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ...
Authors:Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D.
Deposit date:2020-01-15
Release date:2020-03-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020

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