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1HIG
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BU of 1hig by Molmil
THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN INTERFERON-GAMMA.
Descriptor: INTERFERON-GAMMA
Authors:Ealick, S.E, Cook, W.J, Vijay-Kumar, S, Carson, M, Nagabhushan, T.L, Trotta, P.P, Bugg, C.E.
Deposit date:1991-10-03
Release date:1992-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Three-dimensional structure of recombinant human interferon-gamma.
Science, 252, 1991
6GVW
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BU of 6gvw by Molmil
Crystal structure of the BRCA1-A complex
Descriptor: BRCA1-A complex subunit Abraxas 1, BRCA1-A complex subunit RAP80, BRISC and BRCA1-A complex member 1, ...
Authors:Bunker, R.D, Rabl, J, Thoma, N.H.
Deposit date:2018-06-21
Release date:2019-07-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.
Mol.Cell, 75, 2019
6H3C
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BU of 6h3c by Molmil
Cryo-EM structure of the BRISC complex bound to SHMT2
Descriptor: BRISC and BRCA1-A complex member 1, BRISC and BRCA1-A complex member 2, BRISC complex subunit Abraxas 2, ...
Authors:Bunker, R.D, Rabl, J, Thoma, N.H.
Deposit date:2018-07-18
Release date:2019-07-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.
Mol.Cell, 75, 2019
4QTH
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BU of 4qth by Molmil
Crystal structure of anti-uPAR Fab 8B12
Descriptor: anti-uPAR antibody, heavy chain, light chain
Authors:Zhao, B, Yuan, C, Luo, Z, Huang, M.
Deposit date:2014-07-08
Release date:2015-02-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation.
J.Mol.Biol., 427, 2015
4JK1
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BU of 4jk1 by Molmil
X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with Guanosine tetraphosphate (ppGpp)
Descriptor: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ...
Authors:Murakami, K.S.
Deposit date:2013-03-09
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Differential regulation by ppGpp versus pppGpp in Escherichia coli.
Nucleic Acids Res., 41, 2013
4JK2
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BU of 4jk2 by Molmil
X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with guanosine pentaphosphate (pppGpp)
Descriptor: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ...
Authors:Murakami, K.S.
Deposit date:2013-03-09
Release date:2013-04-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.201 Å)
Cite:Differential regulation by ppGpp versus pppGpp in Escherichia coli.
Nucleic Acids Res., 41, 2013
6HL5
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BU of 6hl5 by Molmil
Factor Inhibiting HIF (FIH) in complex with zinc, NOG and ASPP1(932-954)
Descriptor: Apoptosis-stimulating of p53 protein 1, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
Authors:Leissing, T.M, Chowdhury, R, Clifton, I.J, Lu, X, Schofield, C.J.
Deposit date:2018-09-10
Release date:2019-10-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Factor Inhibiting HIF (FIH) in complex with zinc, NOG and ASPP1(932-954)
To Be Published
6O0J
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BU of 6o0j by Molmil
M.tb MenD with ThDP and Inhibitor bound
Descriptor: 1,4-dihydroxy-2-naphthoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ACETATE ION, ...
Authors:Johnston, J.M, Bashiri, G, Bulloch, E.M.M, Jirgis, E.M.N, Nigon, L.V, Chuang, H, Ho, N.A.T, Baker, E.N.
Deposit date:2019-02-16
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
6A35
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BU of 6a35 by Molmil
Crystal structure of 5-methylthioribose 1-phosphate isomerase from Pyrococcus horikoshii OT3 - Form II
Descriptor: Putative methylthioribose-1-phosphate isomerase
Authors:Kanaujia, S.P, Gogoi, P, Mordina, P.
Deposit date:2018-06-14
Release date:2018-12-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural insights into the catalytic mechanism of 5-methylthioribose 1-phosphate isomerase.
J. Struct. Biol., 205, 2019
6A34
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BU of 6a34 by Molmil
Crystal structure of 5-methylthioribose 1-phosphate isomerase from Pyrococcus horikoshii OT3 - Form I
Descriptor: HEXANE-1,6-DIOL, Putative methylthioribose-1-phosphate isomerase
Authors:Kanaujia, S.P, Gogoi, P, Mordina, P.
Deposit date:2018-06-14
Release date:2018-12-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the catalytic mechanism of 5-methylthioribose 1-phosphate isomerase.
J. Struct. Biol., 205, 2019
6O0G
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BU of 6o0g by Molmil
M.tb MenD bound to Intermediate I and Inhibitor
Descriptor: 1,4-dihydroxy-2-naphthoic acid, 2-OXOGLUTARIC ACID, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ...
Authors:Johnston, J.M, Bashiri, G, Bulloch, E.M.M, Jirgis, E.M.N, Chuang, H, Nigon, L.V, Baker, E.N.
Deposit date:2019-02-16
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
7L0E
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BU of 7l0e by Molmil
Crystal structure of bovine RPE65 in complex with gem-difluoro emixustat and palmitate
Descriptor: (1R)-3-amino-1-{3-[(4,4-difluorocyclohexyl)methoxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D.
Deposit date:2020-12-11
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
J.Med.Chem., 64, 2021
3LCB
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BU of 3lcb by Molmil
The crystal structure of isocitrate dehydrogenase kinase/phosphatase in complex with its substrate, isocitrate dehydrogenase, from Escherichia coli.
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isocitrate dehydrogenase [NADP], ...
Authors:Zheng, J, Jia, Z.
Deposit date:2010-01-10
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
Nature, 465, 2010
5JL6
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BU of 5jl6 by Molmil
HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1): ANDROSTENEDIONE COMPLEX #2
Descriptor: 4-ANDROSTENE-3-17-DIONE, Aromatase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ghosh, D, Lo, J, Egbuta, C.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
5JL9
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BU of 5jl9 by Molmil
HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1): ANDROSTENEDIONE COMPLEX #4
Descriptor: 4-ANDROSTENE-3-17-DIONE, Aromatase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ghosh, D, Lo, J, Egbuta, C.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
3LVG
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BU of 3lvg by Molmil
Crystal structure of a clathrin heavy chain and clathrin light chain complex
Descriptor: Clathrin heavy chain 1, Clathrin light chain B
Authors:Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M.
Deposit date:2010-02-20
Release date:2010-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (7.94 Å)
Cite:Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
5JL7
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BU of 5jl7 by Molmil
HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1): ANDROSTENEDIONE COMPLEX #3
Descriptor: 4-ANDROSTENE-3-17-DIONE, Aromatase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ghosh, D, Lo, J, Egbuta, C.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
6N6Q
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BU of 6n6q by Molmil
Crystal structure of a Cytochrome P450 (CYP102L1)
Descriptor: CACODYLATE ION, Cytochrome P450 (CYP102L1), PROTOPORPHYRIN IX CONTAINING FE
Authors:Follmer, A.H, Poulos, T.L.
Deposit date:2018-11-26
Release date:2019-06-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:On the occurrence of cytochrome P450 in viruses.
Proc.Natl.Acad.Sci.USA, 116, 2019
4RUM
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BU of 4rum by Molmil
Crystal structure of the NiCo transition-metal riboswitch bound to cobalt
Descriptor: COBALT (II) ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Ramesh, A, Winkler, W.C.
Deposit date:2014-11-21
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6426 Å)
Cite:Bacterial riboswitches cooperatively bind Ni(2+) or Co(2+) ions and control expression of heavy metal transporters.
Mol.Cell, 57, 2015
5JKV
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BU of 5jkv by Molmil
HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1) AT 2.75 ANGSTROM WITH BOUND POLYETHYLENE GLYCOL
Descriptor: 4-ANDROSTENE-3-17-DIONE, Aromatase, PENTAETHYLENE GLYCOL, ...
Authors:Ghosh, D, Lo, J, Egbuta, C.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
5JKW
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BU of 5jkw by Molmil
HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1) COMPLEXED WITH TESTOSTERONE
Descriptor: Aromatase, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE
Authors:Ghosh, D, Egbuta, C, Lo, J.
Deposit date:2016-04-26
Release date:2017-04-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Testosterone complex and non-steroidal ligands of human aromatase.
J. Steroid Biochem. Mol. Biol., 2018
3LC6
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BU of 3lc6 by Molmil
The alternative conformation structure of isocitrate dehydrogenase kinase/phosphatase from E. Coli
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ...
Authors:Zheng, J, Jia, Z.
Deposit date:2010-01-09
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
Nature, 465, 2010
6Q9V
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BU of 6q9v by Molmil
MSRB3
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Methionine-R-sulfoxide reductase B3, SULFATE ION, ...
Authors:Javitt, G, Fass, D.
Deposit date:2018-12-18
Release date:2020-01-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and Electron-Transfer Pathway of the Human Methionine Sulfoxide Reductase MsrB3.
Antioxid.Redox Signal., 33, 2020
6QA0
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BU of 6qa0 by Molmil
MSRB3 - AA 1-137
Descriptor: CHLORIDE ION, Methionine-R-sulfoxide reductase B3, SULFATE ION, ...
Authors:Javitt, G, Fass, D.
Deposit date:2018-12-18
Release date:2020-01-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.709 Å)
Cite:Structure and Electron-Transfer Pathway of the Human Methionine Sulfoxide Reductase MsrB3.
Antioxid.Redox Signal., 33, 2020
4FGV
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BU of 4fgv by Molmil
Crystal structure of free CRM1 (crystal form 1)
Descriptor: Chromosome region maintenance 1 (CRM1) or Exportin 1 (Xpo1)
Authors:Monecke, T, Neumann, P, Dickmanns, A, Ficner, R.
Deposit date:2012-06-05
Release date:2013-01-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.941 Å)
Cite:Structural basis for cooperativity of CRM1 export complex formation.
Proc.Natl.Acad.Sci.USA, 110, 2013

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