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4FGV

Crystal structure of free CRM1 (crystal form 1)

Summary for 4FGV
Entry DOI10.2210/pdb4fgv/pdb
DescriptorChromosome region maintenance 1 (CRM1) or Exportin 1 (Xpo1) (1 entity in total)
Functional Keywordsheat repeat protein, importin-beta superfamily, nuclear export of numerous protein and rnp cargoes, transport protein
Biological sourceChaetomium thermophilum var. thermophilum DSM 1495
Total number of polymer chains1
Total formula weight124642.15
Authors
Monecke, T.,Neumann, P.,Dickmanns, A.,Ficner, R. (deposition date: 2012-06-05, release date: 2013-01-23, Last modification date: 2023-09-13)
Primary citationMonecke, T.,Haselbach, D.,Voss, B.,Russek, A.,Neumann, P.,Thomson, E.,Hurt, E.,Zachariae, U.,Stark, H.,Grubmuller, H.,Dickmanns, A.,Ficner, R.
Structural basis for cooperativity of CRM1 export complex formation.
Proc.Natl.Acad.Sci.USA, 110:960-965, 2013
Cited by
PubMed: 23277578
DOI: 10.1073/pnas.1215214110
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.941 Å)
Structure validation

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