3LCB

The crystal structure of isocitrate dehydrogenase kinase/phosphatase in complex with its substrate, isocitrate dehydrogenase, from Escherichia coli.

Summary for 3LCB

Related3EPS 3LC6
DescriptorIsocitrate dehydrogenase kinase/phosphatase, Isocitrate dehydrogenase [NADP], ADENOSINE MONOPHOSPHATE, ... (6 entities in total)
Functional Keywordskinase phosphatase, glyoxylate bypass, hydrolaseprotein phosphatase, tricarboxylic acid cycle, isocitrate, transferase, hydrolase
Biological sourceEscherichia coli
Cellular locationCytoplasm  B5Z0A8
Total number of polymer chains4
Total molecular weight229023.65
Authors
Zheng, J.,Jia, Z. (deposition date: 2010-01-10, release date: 2010-04-21, Last modification date: 2017-11-01)
Primary citation
Zheng, J.,Jia, Z.
Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
Nature, 465:961-965, 2010
PubMed: 20505668 (PDB entries with the same primary citation)
DOI: 10.1038/nature09088
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26914 0.3% 10.5% 2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171588
PDB entries from 2020-11-25