3LCB

The crystal structure of isocitrate dehydrogenase kinase/phosphatase in complex with its substrate, isocitrate dehydrogenase, from Escherichia coli.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Isocitrate dehydrogenase kinase/phosphatase	polymer	578	67823.6	2	UniProt (B5Z0A8) Pfam (PF20423) Pfam (PF06315) UniProt (by SIFTS) (Q8X607)	Escherichia coli	IDH kinase/phosphatase, IDHK/P
2	C, D (C, D)	Isocitrate dehydrogenase [NADP]	polymer	416	45809.6	2	UniProt (P08200) Pfam (PF00180)	Escherichia coli	IDH, Oxalosuccinate decarboxylase, NADP(+)-specific ICDH, IDP
3	E, I (A, B)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	2	Chemie (AMP)
4	F, H (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
5	G, J (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	K, L, M, N (A, B, C, D)	water	water		18.0	21	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	227266.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1757.4
All*	Total formula weight	229023.6

*Water molecules are not included.