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7OU0
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BU of 7ou0 by Molmil
The structure of MutS bound to two molecules of ADP-Vanadate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein MutS, MAGNESIUM ION, ...
Authors:Lamers, M.H, Borsellini, A, Friedhoff, P, Kunetsky, V.
Deposit date:2021-06-10
Release date:2022-01-12
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair.
Nat.Struct.Mol.Biol., 29, 2022
7OU2
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BU of 7ou2 by Molmil
The structure of MutS bound to two molecules of ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein MutS
Authors:Lamers, M.H, Borsellini, A, Friedhoff, P, Kunetsky, V.
Deposit date:2021-06-11
Release date:2022-01-12
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair.
Nat.Struct.Mol.Biol., 29, 2022
2FO0
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BU of 2fo0 by Molmil
Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase
Descriptor: 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ...
Authors:Nagar, B, Hantschel, O, Seeliger, M, Davies, J.M, Weis, W.I, Superti-Furga, G, Kuriyan, J.
Deposit date:2006-01-12
Release date:2006-03-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.
Mol.Cell, 21, 2006
7P9O
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BU of 7p9o by Molmil
Structure of E.coli RlmJ in complex with a SAM analogue (CA)
Descriptor: 5'-{[(3S)-3-amino-3-carboxypropyl]amino}-5'-deoxyadenosine, Ribosomal RNA large subunit methyltransferase J
Authors:Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C.
Deposit date:2021-07-27
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.095 Å)
Cite:Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase.
Nucleic Acids Res., 50, 2022
5D8J
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BU of 5d8j by Molmil
Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes.
Descriptor: Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ...
Authors:Doyle, C, Birrane, G.
Deposit date:2015-08-17
Release date:2016-01-13
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
7P8Q
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BU of 7p8q by Molmil
Structure of E.coli RlmJ in complex with an RNA conjugate (GA-SAM)
Descriptor: 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, RNA conjugate (GA-SAM), Ribosomal RNA large subunit methyltransferase J
Authors:Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C.
Deposit date:2021-07-23
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.289 Å)
Cite:Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase.
Nucleic Acids Res., 50, 2022
7P9I
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BU of 7p9i by Molmil
Structure of E.coli RlmJ in complex with an RNA conjugate (GAA-SAM)
Descriptor: 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, RNA conjugate (GAA-SAM), Ribosomal RNA large subunit methyltransferase J
Authors:Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C.
Deposit date:2021-07-27
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.594 Å)
Cite:Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase.
Nucleic Acids Res., 50, 2022
5VF3
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BU of 5vf3 by Molmil
Bacteriophage T4 isometric capsid
Descriptor: Capsid vertex protein gp24, Highly immunogenic outer capsid protein, Major capsid protein, ...
Authors:Chen, Z, Sun, L, Zhang, Z, Fokine, A, Padilla-Sanchez, V, Hanein, D, Jiang, W, Rossmann, M.G, Rao, V.B.
Deposit date:2017-04-06
Release date:2017-09-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the bacteriophage T4 isometric head at 3.3- angstrom resolution and its relevance to the assembly of icosahedral viruses.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5DOL
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BU of 5dol by Molmil
Crystal structure of YabA amino-terminal domain from Bacillus subtilis
Descriptor: Initiation-control protein YabA
Authors:Cherrier, M.V, Bazin, A, Jameson, K.H, Wilkinson, A.J, Noirot-Gros, M.F, Terradot, L.
Deposit date:2015-09-11
Release date:2016-01-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Tetramerization and interdomain flexibility of the replication initiation controller YabA enables simultaneous binding to multiple partners.
Nucleic Acids Res., 44, 2016
5WTA
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BU of 5wta by Molmil
Crystal Structure of Staphylococcus aureus SdrE apo form
Descriptor: Serine-aspartate repeat-containing protein E
Authors:Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X.
Deposit date:2016-12-10
Release date:2017-07-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
5E05
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BU of 5e05 by Molmil
Structure of Sin Nombre virus nucleoprotein in shot-axis crystal form
Descriptor: Nucleocapsid protein, PHOSPHATE ION
Authors:Guo, Y, Wang, W.M, Lou, Z.Y.
Deposit date:2015-09-28
Release date:2015-12-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation
J.Virol., 90, 2015
5V7M
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BU of 5v7m by Molmil
PCNA mutant L126A/I128A Protein Defective in Gene Silencing
Descriptor: MAGNESIUM ION, Proliferating cell nuclear antigen
Authors:Kondratick, C.M, Litman, J.M, Washington, M.T, Dieckman, L.M.
Deposit date:2017-03-20
Release date:2018-03-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structures of PCNA mutant proteins defective in gene silencing suggest a novel interaction site on the front face of the PCNA ring.
PLoS ONE, 13, 2018
5UJ8
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BU of 5uj8 by Molmil
Human Origin Recognition Complex subunits 2 and 3
Descriptor: Origin recognition complex subunit 2, Origin recognition complex subunit 3
Authors:Tocilj, A, On, K.F, Elkayam, E, Joshua-Tor, L.
Deposit date:2017-01-17
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6 Å)
Cite:Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
Elife, 6, 2017
2IHN
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BU of 2ihn by Molmil
Co-crystal of Bacteriophage T4 RNase H with a fork DNA substrate
Descriptor: 5'-D(*CP*TP*AP*AP*CP*TP*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*CP*C)-3', 5'-D(*GP*GP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*TP*AP*GP*TP*CP*AP*A)-3', Ribonuclease H
Authors:Devos, J.M, Mueser, T.C.
Deposit date:2006-09-26
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how FEN-1 family nucleases bind their substrates.
J.Biol.Chem., 282, 2007
5E04
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BU of 5e04 by Molmil
Crystal structure of Andes virus nucleoprotein
Descriptor: Nucleoprotein
Authors:Guo, Y, Wang, W.M, Lou, Z.Y.
Deposit date:2015-09-28
Release date:2015-12-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation
J.Virol., 90, 2015
5E0T
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BU of 5e0t by Molmil
Human PCNA mutant - S228I
Descriptor: Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6653 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5V2S
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BU of 5v2s by Molmil
Crystal structure of glycoprotein B from Herpes Simplex Virus type I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B
Authors:Cooper, R.S, Heldwein, E.E.
Deposit date:2017-03-06
Release date:2018-05-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for membrane anchoring and fusion regulation of the herpes simplex virus fusogen gB.
Nat. Struct. Mol. Biol., 25, 2018
5E06
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BU of 5e06 by Molmil
Structure of Sin Nombre virus nucleoprotein in long-axis crystal form
Descriptor: Nucleocapsid protein
Authors:Guo, Y, Wang, W.M, Lou, Z.Y.
Deposit date:2015-09-28
Release date:2015-12-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation
J.Virol., 90, 2015
5X06
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BU of 5x06 by Molmil
DNA replication regulation protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit beta, DnaA regulatory inactivator Hda, ...
Authors:Kim, J, Cho, Y.
Deposit date:2017-01-20
Release date:2018-01-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.237 Å)
Cite:Replication regulation protein
To Be Published
5WCE
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BU of 5wce by Molmil
Caulobacter crescentus pol III beta
Descriptor: DNA polymerase III subunit beta
Authors:Oakley, A.J.
Deposit date:2017-06-30
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Pol III beta from Caulobacter crescentus
To Be Published
5V7K
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BU of 5v7k by Molmil
PCNA mutant D41A/D42A Protein Defective in Gene Silencing
Descriptor: Proliferating cell nuclear antigen
Authors:Kondratick, C.M, Litman, J.M, Washington, M.T, Dieckman, L.M.
Deposit date:2017-03-20
Release date:2018-03-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structures of PCNA mutant proteins defective in gene silencing suggest a novel interaction site on the front face of the PCNA ring.
PLoS ONE, 13, 2018
5WTB
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BU of 5wtb by Molmil
Complex Structure of Staphylococcus aureus SdrE with human complement factor H
Descriptor: Peptide from Complement factor H, Serine-aspartate repeat-containing protein E
Authors:Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X.
Deposit date:2016-12-10
Release date:2017-07-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
2FJA
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BU of 2fja by Molmil
adenosine 5'-phosphosulfate reductase in complex with substrate
Descriptor: ADENOSINE-5'-PHOSPHOSULFATE, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ...
Authors:Schiffer, A, Fritz, G, Kroneck, P.M, Ermler, U.
Deposit date:2006-01-02
Release date:2006-03-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states
Biochemistry, 45, 2006
2CIS
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BU of 2cis by Molmil
Structure-based functional annotation: Yeast ymr099c codes for a D- hexose-6-phosphate mutarotase. Complex with tagatose-6-phosphate
Descriptor: 6-O-phosphono-beta-D-tagatofuranose, BARIUM ION, GLUCOSE-6-PHOSPHATE 1-EPIMERASE
Authors:Graille, M, Baltaze, J.-P, Leulliot, N, Liger, D, Quevillon-Cheruel, S, van Tilbeurgh, H.
Deposit date:2006-03-24
Release date:2006-07-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure-based functional annotation: yeast ymr099c codes for a D-hexose-6-phosphate mutarotase.
J. Biol. Chem., 281, 2006
2CIR
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BU of 2cir by Molmil
Structure-based functional annotation: Yeast ymr099c codes for a D- hexose-6-phosphate mutarotase. Complex with glucose-6-phosphate
Descriptor: 6-O-phosphono-beta-D-glucopyranose, HEXOSE-6-PHOSPHATE MUTAROTASE
Authors:Graille, M, Baltaze, J.-P, Leulliot, N, Liger, D, Quevillon-Cheruel, S, van Tilbeurgh, H.
Deposit date:2006-03-24
Release date:2006-07-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-based functional annotation: yeast ymr099c codes for a D-hexose-6-phosphate mutarotase.
J. Biol. Chem., 281, 2006

223532

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