5E0T

Human PCNA mutant - S228I

Summary for 5E0T

Related1VYM 5E0V 5E0U
DescriptorProliferating cell nuclear antigen (2 entities in total)
Functional Keywordsdna replication, dna binding protein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  P12004
Total number of polymer chains3
Total molecular weight86465.49
Authors
Duffy, C.M.,Hilbert, B.J.,Kelch, B.A. (deposition date: 2015-09-29, release date: 2016-04-20, Last modification date: 2017-11-22)
Primary citation
Duffy, C.M.,Hilbert, B.J.,Kelch, B.A.
A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428:1023-1040, 2016
PubMed: 26688547 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2015.11.029
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6653 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23060.4%3.5%4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5e0t
no rotation
Molmil generated image of 5e0t
rotated about x axis by 90°
Molmil generated image of 5e0t
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 5e0t
no rotation
Molmil generated image of 5e0t
rotated about x axis by 90°
Molmil generated image of 5e0t
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (5e0t.pdb1.gz [123.11 KB])
Coordinate files for Biological unit (5e0t.pdb2.gz [243.25 KB])