5E0U

Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms

Summary for 5E0U

Related1AXC 5E0T 5E0V
DescriptorProliferating cell nuclear antigen, Cyclin-dependent kinase inhibitor 1 (3 entities in total)
Functional Keywordsdna replication, sliding clamp, dna binding protein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  P12004
Cytoplasm P38936
Total number of polymer chains6
Total molecular weight95112.62
Authors
Duffy, C.M.,Hilbert, B.J.,Kelch, B.A. (deposition date: 2015-09-29, release date: 2016-04-20, Last modification date: 2017-11-22)
Primary citation
Duffy, C.M.,Hilbert, B.J.,Kelch, B.A.
A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428:1023-1040, 2016
PubMed: 26688547 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2015.11.029
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.93 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2171701.0%0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5e0u
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Molmil generated image of 5e0u
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Molmil generated image of 5e0u
rotated about y axis by 90°
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