5E0U
Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Proliferating cell nuclear antigen | polymer | 261 | 28821.8 | 3 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) In PDB | Homo sapiens (Human) | PCNA,Cyclin |
2 | D, E, F | Cyclin-dependent kinase inhibitor 1 | polymer | 23 | 2882.4 | 3 | UniProt (P38936) In PDB | Homo sapiens | CDK-interacting protein 1,Melanoma differentiation-associated protein 6,MDA-6,p21 |
3 | water | water | 18.0 | 701 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 261 (UniProt: P12004)
D, E, F: 139 - 160 (UniProt: P38936)
PDB | External Database | Details |
---|---|---|
Ile 228 | Ser 228 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Cys 138 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 95112.6 | |
All* | Total formula weight | 95112.6 |