5E0U

Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Proliferating cell nuclear antigen	polymer	261	28821.8	3	UniProt (P12004) Pfam (PF00705) Pfam (PF02747)	Homo sapiens (Human)	PCNA,Cyclin
2	D, E, F (D, E, F)	Cyclin-dependent kinase inhibitor 1	polymer	23	2882.4	3	UniProt (P38936)	Homo sapiens	CDK-interacting protein 1,Melanoma differentiation-associated protein 6,MDA-6,p21
3	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	701	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 261 (UniProt: P12004)

PDB	External Database	Details
Ile 228	Ser 228	engineered mutation

D, E, F: 139 - 160 (UniProt: P38936)

PDB	External Database	Details
Cys 138	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	95112.6
All*	Total formula weight	95112.6

*Water molecules are not included.