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5E0U

Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CProliferating cell nuclear antigenpolymer26128821.83UniProt (P12004)
Pfam (PF00705)
Pfam (PF02747)
In PDB
Homo sapiens (Human)PCNA,Cyclin
2D, E, FCyclin-dependent kinase inhibitor 1polymer232882.43UniProt (P38936)
In PDB
Homo sapiensCDK-interacting protein 1,Melanoma differentiation-associated protein 6,MDA-6,p21
3waterwater18.0701Chemie (HOH)
Sequence modifications
A, B, C: 1 - 261 (UniProt: P12004)
PDBExternal DatabaseDetails
Ile 228Ser 228engineered mutation
D, E, F: 139 - 160 (UniProt: P38936)
PDBExternal DatabaseDetails
Cys 138-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight95112.6
All*Total formula weight95112.6
*Water molecules are not included.

225158

PDB entries from 2024-09-18

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