7P8Q

Structure of E.coli RlmJ in complex with an RNA conjugate (GA-SAM)

Summary for 7P8Q

• Entry DOI: 10.2210/pdb7p8q/pdb
• Related: 6QDX
• Descriptor: Ribosomal RNA large subunit methyltransferase J, RNA conjugate (GA-SAM), 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, ... (4 entities in total)
• Functional Keywords: rna mtases, methyltransferase, sam analogue, m6a, rna binding, sam conjugate, rlmj, conjugate analogue, rna recognition, bisubstrate analogue, rna binding protein
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 2
• Total formula weight: 32963.54

Authors

Meynier, V.,Catala, M.,Oerum, S.,Barraud, P.,Tisne, C. (deposition date: 2021-07-23, release date: 2022-06-01, Last modification date: 2024-01-31)

• Primary citation: Meynier, V.,Iannazzo, L.,Catala, M.,Oerum, S.,Braud, E.,Atdjian, C.,Barraud, P.,Fonvielle, M.,Tisne, C.,Etheve-Quelquejeu, M.; Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase.; Nucleic Acids Res., 50:5793-5806, 2022; PubMed: 35580049; DOI: 10.1093/nar/gkac354

Experimental method

X-RAY DIFFRACTION (2.289 Å)