8BGF
 
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5LSW
 | | A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell differentiation protein RCD1 homolog, LD12033p, ... | | Authors: | Sgromo, A, Raisch, T, Bawankar, P, Bhandari, D, Chen, Y, Kuzuoglu-Ozturk, D, Weichenrieder, O, Izaurralde, E. | | Deposit date: | 2016-09-05 | | Release date: | 2017-02-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.
Nat Commun, 8, 2017
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8IIC
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8IIB
 | | Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546) | | Descriptor: | CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Fang, X, Lu, G, Hou, C, Gong, P. | | Deposit date: | 2023-02-24 | | Release date: | 2023-06-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding.
Virol Sin, 38, 2023
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6M6A
 | | Cryo-EM structure of Thermus thermophilus Mfd in complex with RNA polymerase | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Shi, J, Wen, A, Feng, Y. | | Deposit date: | 2020-03-14 | | Release date: | 2020-10-14 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Structural basis of Mfd-dependent transcription termination.
Nucleic Acids Res., 48, 2020
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5D4E
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8WIL
 | | Crystal structure of Jingmen tick virus RNA-dependent RNA polymerase (D55 construct) | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Jingmen tick virus NSP1, ... | | Authors: | Wang, X, Jing, X, Deng, F, Gong, P. | | Deposit date: | 2023-09-24 | | Release date: | 2024-01-17 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A jingmenvirus RNA-dependent RNA polymerase structurally resembles the flavivirus counterpart but with different features at the initiation phase.
Nucleic Acids Res., 52, 2024
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6JBQ
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6M6B
 | | Cryo-EM structure of Thermus thermophilus Mfd in complex with RNA polymerase and ATP-gamma-S | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Shi, J, Wen, A, Feng, Y. | | Deposit date: | 2020-03-14 | | Release date: | 2020-10-14 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis of Mfd-dependent transcription termination.
Nucleic Acids Res., 48, 2020
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5NSF
 | | Structure of AzuAla | | Descriptor: | (2~{S})-2-azanyl-3-(2,6-dihydroazulen-1-yl)propanoic acid, CALCIUM ION, GLYCEROL, ... | | Authors: | Martins, B.M. | | Deposit date: | 2017-04-26 | | Release date: | 2019-01-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.426 Å) | | Cite: | Site-Resolved Observation of Vibrational Energy Transfer Using a Genetically Encoded Ultrafast Heater.
Angew. Chem. Int. Ed. Engl., 58, 2019
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2BA1
 | | Archaeal exosome core | | Descriptor: | Archaeal exosome RNA binding protein CSL4, Archaeal exosome complex exonuclease RRP41, Archaeal exosome complex exonuclease RRP42, ... | | Authors: | Hopfner, K.P, Buttner, K, Wenig, K. | | Deposit date: | 2005-10-13 | | Release date: | 2005-11-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural framework for the mechanism of archaeal exosomes in RNA processing.
Mol.Cell, 20, 2005
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4TYN
 | | DEAD-box helicase Mss116 bound to ssDNA and ADP-BeF | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, mitochondrial, ... | | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | | Deposit date: | 2014-07-08 | | Release date: | 2014-12-31 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.959 Å) | | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
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6KLE
 | | Monomeric structure of Machupo virus polymerase bound to vRNA promoter | | Descriptor: | MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... | | Authors: | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | | Deposit date: | 2019-07-30 | | Release date: | 2020-03-18 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structural insight into arenavirus replication machinery.
Nature, 579, 2020
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4KHT
 | | Triple helix bundle of GP41 complexed with fab 8066 | | Descriptor: | 8066 heavy chain, 8066 light chain, Gp41 helix | | Authors: | Li, M, Gustchina, A, Wlodawer, A. | | Deposit date: | 2013-05-01 | | Release date: | 2014-03-12 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.817 Å) | | Cite: | Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Plos One, 8, 2013
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7QE0
 | | 80S-bound human SKI complex in the open state | | Descriptor: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*U)-3') | | Authors: | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | | Deposit date: | 2021-12-01 | | Release date: | 2022-02-09 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism.
Mol.Cell, 82, 2022
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1U9S
 | | Crystal structure of the specificity domain of Ribonuclease P of the A-type | | Descriptor: | BARIUM ION, RIBONUCLEASE P | | Authors: | Krasilnikov, A.S, Xiao, Y, Pan, T, Mondragon, A. | | Deposit date: | 2004-08-10 | | Release date: | 2004-10-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Basis for structural diversity in homologous RNAs.
Science, 306, 2004
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4KHX
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4KI5
 | | Cystal structure of human factor VIII C2 domain in a ternary complex with murine inhbitory antibodies 3E6 and G99 | | Descriptor: | Coagulation factor VIII, MURINE MONOCLONAL 3E6 FAB HEAVY CHAIN, MURINE MONOCLONAL 3E6 FAB LIGHT CHAIN, ... | | Authors: | Walter, J.D, Meeks, S.L, Healey, J.F, Lollar, P, Spiegel, P.C. | | Deposit date: | 2013-05-01 | | Release date: | 2014-01-15 | | Method: | X-RAY DIFFRACTION (2.47 Å) | | Cite: | Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes.
Blood, 122, 2013
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6RID
 | | Structure of Vaccinia Virus DNA-dependent RNA polymerase elongation complex | | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | | Authors: | Hillen, H.S, Bartuli, J, Grimm, C, Dienemann, C, Bedenk, K, Szalar, A, Fischer, U, Cramer, P. | | Deposit date: | 2019-04-23 | | Release date: | 2019-12-18 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes.
Cell, 179, 2019
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5W5H
 | | Human IFIT1 dimer with m7Gppp-AAAA | | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3') | | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | Deposit date: | 2017-06-15 | | Release date: | 2017-07-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published
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5WU6
 | | Crystal structure of apo human Tut1, form IV | | Descriptor: | MAGNESIUM ION, Speckle targeted PIP5K1A-regulated poly(A) polymerase | | Authors: | Yamashita, S, Tomita, K. | | Deposit date: | 2016-12-16 | | Release date: | 2017-05-31 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.209 Å) | | Cite: | Crystal structures of U6 snRNA-specific terminal uridylyltransferase
Nat Commun, 8, 2017
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6SJ7
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8I9J
 | | The PKR and E3L complex | | Descriptor: | Interferon-induced, double-stranded RNA-activated protein kinase, RNA-binding protein E3 | | Authors: | Han, C.W, Kim, H.J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-06-28 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (6.39 Å) | | Cite: | Structural study of novel vaccinia virus E3L and dsRNA-dependent protein kinase complex.
Biochem.Biophys.Res.Commun., 665, 2023
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7ELC
 | | Structure of monomeric complex of MACV L bound to Z and 3'-vRNA | | Descriptor: | 3'-vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... | | Authors: | Xu, X, Peng, R, Peng, Q, Shi, Y. | | Deposit date: | 2021-04-09 | | Release date: | 2021-05-05 | | Last modified: | 2021-07-14 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
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7EL9
 | | Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex) | | Descriptor: | MANGANESE (II) ION, Machupo virus 3'-vRNA promoter, RING finger protein Z, ... | | Authors: | Peng, R, Xu, X, Peng, Q, Shi, Y. | | Deposit date: | 2021-04-09 | | Release date: | 2021-05-05 | | Last modified: | 2021-07-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
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