7EL9
Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex)
Summary for 7EL9
Entry DOI | 10.2210/pdb7el9/pdb |
EMDB information | 31177 |
Descriptor | RNA-directed RNA polymerase L, RING finger protein Z, Machupo virus 3'-vRNA promoter, ... (5 entities in total) |
Functional Keywords | rna virus, polymerase, replication, transcription, matrix protein, viral protein-rna complex, viral protein/rna |
Biological source | Machupo mammarenavirus (MACV) More |
Total number of polymer chains | 6 |
Total formula weight | 534925.10 |
Authors | |
Primary citation | Xu, X.,Peng, R.,Peng, Q.,Wang, M.,Xu, Y.,Liu, S.,Tian, X.,Deng, H.,Tong, Y.,Hu, X.,Zhong, J.,Wang, P.,Qi, J.,Gao, G.F.,Shi, Y. Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6:921-931, 2021 Cited by PubMed: 34127846DOI: 10.1038/s41564-021-00916-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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